Nocturnal HD Protects Bones Better Than Standard HD

Compared to 52 patients on conventional HD, 36 patients on nocturnal HD had better bone mineral density at the lumbar spine, femoral neck, and hip after one year.

Read the abstract » | (added 2016-06-08)

Tags: Hemodialysis

Mineral balance in long HD

A metaanalysis from Canada of 21 studies concluded that keeping dialysate calcium ≥1.5 mmol/L for most patients on long/long-frequent HD prevents an increase in PTH levels and a decline in bone mineral density—without raising the risk of calcification. Adding phosphate to the dialysate for those with a low predialysis level or very low level makes sense.

Read the abstract » | (added 2013-08-22)

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Alternate-night HD improves bone minerals & blood pressure

Among 63 people in Australia who switched from standard HD to alternate-night HD, bone mineral balance and blood pressure improved after 18–24 months. Left ventricular mass did not improve, but remained stable.

Read the abstract » | (added 2011-11-28)

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Nocturnal HD improves bone mineral levels

Yes, we knew this—but this time, it's a randomized controlled trial of nocturnal (6 nights/week) vs. standard in-center HD (3 times/week). Compared to standard HD, those doing nocturnal had lower phosphorus—even without binders—lower PTH levels, and lower calcium-times-phosphorus products.

Read the abstract » | (added 2011-02-24)

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Nocturnal HD helps bone mineral status

Doing nocturnal home HD every other night helps bone minerals stay at more normal levels than standard treatments, say researchers from Australia in a new study. After 26 patients switched from standard (home) to nocturnal HD, their serum phosphorus and calcium-phosphorus products fell, most needed no binders, and bone mineral density was stable. Plus, blood vessel calcification improved or at least was stable in 87.5%.

Read the abstract » | (added 2011-02-24)

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