Journal Watch - PD

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  • Cardiovascular Outcomes Compared in PD vs. Home HD

    Data from almost 69,000 patients in the USRDS who started PD or home HD to assess for rates of hospitalizations due to incident cardiovascular events (acute coronary syndrome, heart failure, stroke). While the unadjusted rate of cardiovascular events was higher in home HD than PD patients, the adjusted rates were lower for stroke and acute coronary syndrome. There was no difference in heart failure risk, but home HD was linked with a 22% lower adjusted risk of cardiovascular death.

    Read the abstract » | (added 2024-02-07)

    Tags: USRDS, PD, Home HD, Hospitalization Rate, Incident Cardiovascular Events

  • The PD Surprise Question Predicts Transfer to HD

    An observational study of 1,275 PD patients in 35 programs asking the RN and treating nephrologist, “Would you be surprised if this patient transferred to HD in the next 6 months?” identified 15% as high risk. After 6 months, the transfer to HD rate was nearly four times higher in the high risk group than the low risk group.

    Read the abstract » | (added 2023-12-15)

    Tags: PD, Home Dialysis, Peritoneal Dialysis, Surprise Question

  • Steady Glucose Concentration in PD and Sodium Removal

    In a small pilot study (n=8), two fast-average and six fast transporters used a standard 4-hour CAPD dwell as a control, and three 5-hour steady-concentration treatments using the Carry Life® UF device following an overnight icodextrin fill as the intervention. UF rates were significantly higher with the steady glucose concentration treatments, as were sodium removal and glucose UF efficiency.

    Read the abstract » | (added 2023-11-15)

    Tags: PD, Glucose Concentration, Sodium Removal

  • Exercise and Quality of Life on PD

    In a cross sectional study of 339 PD patients, 81.7% exercised a median of 5 hours per week, mainly slow walking. Those who exercised had better quality of life. Older age, female sex, higher BMI, and pain were independently associated with lower exercise capacity.

    Read the abstract » | (added 2023-10-13)

    Tags: PD, Exercise, Quality Of Life

  • Outcomes with PD to HHD Compared to Direct HHD

    Analysis of data from all patients who started PD or HHD in the first 90 days of kidney replacement therapy in Canada matched PD+HHD patients (n=163) 1:1 to incident HHD patients (n=711). Interestingly, while hospitalization risk was similar, clinical outcomes were better in the PD+HHD group.

    Read the abstract » | (added 2023-09-13)

    Tags: PD, HHD, Kidney Replacement Therapy, Clinical Outcomes

  • Systemic Immune-Inflammation Index (SII) and Mortality on PD

    Among 1,419 PD patients from 2007 to 2019, SII was calculated as platelet count x neutrophil count/lymphocyte count. During a median 42 month follow up, 321 patients died, 171 of cardiovascular disease. Each 1 standard deviation increase in the SII was associated with a 20.2% rise in all-cause mortality and 28% in cardiovascular-specific mortality.

    Read the abstract » | (added 2023-09-13)

    Tags: PD, Mortality, Systemic Immune inflammation Index

  • ISPD Proposes to Remove PD Toxin Clearance Targets

    New ISPD Guidelines suggest that the focus of PD should be patient well-being—not lab values. This change would allow more people to do PD, and focusing on relieving uremic symptoms could help determine which solutes really do matter to quality of life.

    Read the abstract » | (added 2023-08-16)

    Tags: PD, Patient Well being, Lab Values, Uremic Symptoms, Quality Of Life

  • Hope Matters in PD

    Among 134 patients receiving PD in Hong Kong, those who were working, had a higher income, and were using a cycler for PD had higher hope scores, and there were correlations with age and social support. Higher hope scores were linked with better mental well-being and less severe depression.

    Read the abstract » | (added 2023-06-14)

    Tags: PD, PD Cycler, Work, Hope Score, Social Support, Mental Well being, Depression

  • UK Target: 20+% on Home Dialysis

    Despite the many benefits of home therapies, PD and home HD remain underused. The UK now recommends a minimum 20% prevalence rate for home dialysis.

    Read the abstract » | (added 2023-06-14)

    Tags: PD, Home HD, Peritonitis

  • Serum Phosphorus and Survival on PD

    Data from 5,847 PD patients between 2014-2017 from seven countries in the PDOPPS study found that compared to an optimal range of 3.5-4.5mg/dL, the hazard ratio (HR) for all-cause mortality was 19% higher when phosphorus was 5.5-6.5 and 53% higher when phosphorus was greater than 6.5. When 6 months of data were examined, the linkage was even stronger.

    Read the abstract » | (added 2023-02-13)

    Tags: PD, Serum Phosphorus, PDOPPS, Hazard Ratio, All cause Mortality