Meta-analysis of PD Remote Patient Monitoring

Analysis of data from 22 studies revealed that remote monitoring for PD reduced technique failure, hospitalization, and mortality vs. traditional PD monitoring.

Read the abstract » | (added 2023-04-19)

Tags: Remote Monitoring, PD, Technique Failure, Hospitalization, Mortality, Traditional PD Monitoring

Serum Phosphorus and Survival on PD

Data from 5,847 PD patients between 2014-2017 from seven countries in the PDOPPS study found that compared to an optimal range of 3.5-4.5mg/dL, the hazard ratio (HR) for all-cause mortality was 19% higher when phosphorus was 5.5-6.5 and 53% higher when phosphorus was greater than 6.5. When 6 months of data were examined, the linkage was even stronger.

Read the abstract » | (added 2023-02-13)

Tags: PD, Serum Phosphorus, PDOPPS, Hazard Ratio, All cause Mortality

Cycler vs. Manual PD for Survival

A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.

Read the abstract » | (added 2022-12-19)

Tags: Peritoneal Dialysis, PD, Modality, Automated Peritoneal Dialysis, APD, Continuous Ambulatory Peritoneal Dialysis, CAPD, All cause Mortality, ACM, PD Failure, Survival

The Predictive Value of Early, Non-infectious PD Complications

A prospective, multicenter cohort study of 1,596 people starting PD in New Zealand from 2014 to 2018 (inclusive) looked at survival and time on PD of those who had catheter-related exit site dialysate leaks or other leaks within 30 days of PD start. Peritonitis-free survival, first PD catheter survival, and tunnel infection free survival were secondary outcomes. Among the 102 with an early complication, overall mortality, the rate of stopping PD, and first catheter failure were all higher.

Read the abstract » | (added 2022-11-16)

Tags: PD, Survival, Peritonitis free Survival, First PD Catheter Survival, Tunnel Infection Free Survival, Early Catheter related Complication

Better COVID Survival with PD and Home HD

Among 1,336 people whose kidneys failed between March, 2020 and January, 2021, 13.12% (n=178) contracted COVID-19. Of these, most (n=139) did standard in-center HD, and 33 (3.87%) died. On PD, 39 people developed COVID, and 1 (0.81%) died. On home HD, there were zero cases of COVID and no deaths. Five transplant patients developed COVID, with a mortality rate of 1.47%.

Read the abstract » | (added 2022-10-17)

Tags: Covid, Standard In center HD, PD, Mortality, Home HD, Home Hd And Covid, Transplant

HD Dose and Patient Survival: More is Better

Even using spKt/V—a flawed measure that considers only urea—a study of 558 standard HD patients from 2015 to 2020, of whom 214 died, found that a higher dose of dialysis reduced the risk of all-cause mortality by 33%.

Read the abstract » | (added 2022-09-13)

Tags: HD Dose, Dialysis Dose, Patient Survival, All cause Mortality

Too-high OR Too-low LDL Cholesterol and Survival on PD

A retrospective study in China looked at data from 3,565 people starting PD from 2005 to 2020. Both higher and lower levels of LDL-C were linked with higher all-cause and cardiovascular mortality. Malnutrition and low LDL-C was especially risky.

Read the abstract » | (added 2022-08-11)

Tags: PD, LDL C, Cardiovascular Mortality, All cause Mortality, Malnutrition

Structured CKD Education More Than Tripled Uptake of Home Therapies

In a matched retrospective cohort study, 2,398 CKD patients who attended a single 90-minute education program were pair-matched with others who did not. Compared to controls, those who attended the session were significantly more likely to be doing home dialysis (38.5% vs. 12.6%) and to be using a permanent access (57.9% vs. 33.8%). Hospitalization rates were 38% lower as well, and education-attendees had lower first-year mortality.

Read the abstract » | (added 2022-07-13)

Tags: CKD, Education Program, Home Dialysis, Permanent Access, Hospitalization Rates, First year Mortality

Fatigue at PD Start Linked with Higher Mortality

A PLOS One study compared 4,285 incident PD patients who completed a KDQOL-SF vitality scale from Brazil (1,388) and the U.S. (2,897) from 2004 to 2011. Lower vitality scores after 90 days of PD were linked with a higher risk of mortality in both countries

Read the abstract » | (added 2022-07-13)

Tags: Fatigue, Incident Peritoneal Dialysis, Vitality, Mortality

In Which Countries Do People Stay on PD Longer?

The Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) analyzed time on PD among 218 randomly chosen clinics and 7,121 patients in seven countries including the U.S. Median time on PD ranged from 1.7 years in the UK to 3.2 years in Japan and Thailand. PD mortality risk was higher in Thailand and the U.S., and infection was the leading cause of transfers to HD.

Read the abstract » | (added 2022-06-10)

Tags: Peritoneal Dialysis Outcomes And Practice Patterns Study, PDOPPS, PD, Mortality, Hemodialysis Transfer, Kidney Transplantation