Savings from Incremental PD

In a stud of 147 people who did incremental PD from 2009 through 2021, 11.9% transitioned to full-dose PD. Peritoneal glucose exposure was reduced by multiple kilos per year, and costs, plastic waste, and water use were also lower, as was time to manage PD.

Read the abstract » | (added 2022-10-17)

Tags: Healthcare Cost, Cost Analysis, Incremental PD, Full dose PD, Peritoneal Glucose Exposure

PD: Sweat it Out to Reduce Fluid Overload

In a small study, 4 people on PD used a portable sauna bath daily for 10 days, at 30 minutes a day and a temperature of 45°C. Most (51) of the 54 sauna sessions were well-tolerated; two people reported dizziness and one person with advanced diabetic neuropathy received a second degree skin burn. Body water loss and blood pressure improved significantly from the control period. Larger studies are needed.

Read the abstract » | (added 2022-10-17)

Tags: Diaphoresis, Fluid Overload, Sauna Bath, Sweat

Remote vs. In-person PD Training: Which is Better?

It’s a tie, finds a small, retrospective Italian study comparing 21 in-home, in-person PD trainings from 2014 through 2016 to 25 video-based training from 2016 through 2018. After a home visit, PD training done by telemedicine. Actually, there were 5 episodes of peritonitis in the home training group—and 0 in the telemedicine group. And, 2-year technique survival with in-person training was 56.3%—while for telemedicine training, it was 76.9%.

Read the abstract » | (added 2022-10-17)

Tags: Remote Training, PD Training, Telemedicine

Better COVID Survival with PD and Home HD

Among 1,336 people whose kidneys failed between March, 2020 and January, 2021, 13.12% (n=178) contracted COVID-19. Of these, most (n=139) did standard in-center HD, and 33 (3.87%) died. On PD, 39 people developed COVID, and 1 (0.81%) died. On home HD, there were zero cases of COVID and no deaths. Five transplant patients developed COVID, with a mortality rate of 1.47%.

Read the abstract » | (added 2022-10-17)

Tags: Covid, Standard In center HD, PD, Mortality, Home HD, Home Hd And Covid, Transplant

The Varied Uses of Assisted PD in Spain

In a retrospective look from 1997 through 2020, a Spanish clinic identified four groups who used assisted PD at some point. Group 1 was totally dependent at PD start, group 2 was self-care and then became totally dependent, group 3 needed short-term PD help, and group 4, the controls, remained on self-care. Of those who required assistance, 73% did so during follow up, not initially. Up to 44% of autonomous patients became dependent for various reasons over time, including loss of a care partner. Assisted PD—even when paying care partners—was less costly than switching to standard HD.

Read the abstract » | (added 2022-10-17)

Tags: Assisted PD, Dependency

Impact of Telemedicine on PD Technique Survival

Can telemedicine (TM) help people stay on PD longer? A prospective study conducted in 27 hospitals in China since 2016 enrolled 7,539 patients. Compared to matched patients in the non-TM group (60.9%), those in the TM group (39.1%) had significantly lower risks of severe fluid overload, inadequate solute clearance, non-infectious catheter complications, transfer to HD, and death.

Read the abstract » | (added 2022-09-13)

Tags: Telemedicine, PD, Technique Survival, Fluid Overload, Inadequate Solute Clearance, Non infectious Catheter Complications

HD Dose and Patient Survival: More is Better

Even using spKt/V—a flawed measure that considers only urea—a study of 558 standard HD patients from 2015 to 2020, of whom 214 died, found that a higher dose of dialysis reduced the risk of all-cause mortality by 33%.

Read the abstract » | (added 2022-09-13)

Tags: HD Dose, Dialysis Dose, Patient Survival, All cause Mortality

Replacing Dextrose in PD Fluid—with Steviol Glycosides?

Using glucose to remove water will scar the peritoneum over time—making PD a short-term option for most. Icodextrin (Extraneal®) is a glucose-free alternative. Now, researchers are looking at another one: steviol glycosides (SG), the compounds that make stevia taste sweet. Using artificial membranes and mice, dialysate with 1.5%, 1%, and even 0.75% SG had similar results as glucose-based fluids—with better biocompatibility.

Read the abstract » | (added 2022-09-13)

Tags: Dextrose, PD Fluid, Steviol Glycosides, Icodextrin

Safety of Exercise for Those Who Do PD

A review of 25 studies of exercise in PD found only minor adverse events, mainly short-term muscle or joint pain or fatigue. There were no serious adverse events or signs of harm.

Read the abstract » | (added 2022-09-13)

Tags: PD, Peritoneal Dialysis, Exercise, Benefits, Adverse Events

Meta-analysis: Buttonhole vs. Rope Ladder Cannulation

Buttonhole cannulation with blunt needles can make home hemodialysis more appealing. A new systematic review and meta-analysis of 15 well-designed studies found that Buttonhole cannulation significantly reduced aneurysms, stenosis, blood clots, and bruising—with no difference in infection.

Read the abstract » | (added 2022-08-11)

Tags: Buttonhole Cannulation, Blunt Needles, Rope ladder Cannulation, Arteriovenous Fistula Puncture Techniques