Journal Watch

  • Protein Clearance Predicts Mortality on PD

    Protein clearance on PD may be a marker of peritoneal inflammation. Among 711 PD patients followed for at least one year, each 10mL/day rise in protein clearance was linked with a 10.4% increase in the risk of all-cause mortality (p=0.008). Protein clearance was linked with serum albumin and C-reactive protein levels.

    Read the abstract » | (added 2018-12-14)

  • Longer-term Benefits of Early Start PD

    Do people who start PD emergently differ from those with a planned PD start? No, suggests a new study of 154 patients followed for a median of just over a year. Early vs. planned-start patients had similar ages, BMIs, genders, and rates PD drop-out due to peritonitis, catheter dysfunction, and burnout. Only diabetes and BMI >25 were independently associated with PD technique failure—but no differences were found between early and planned starts.

    Read the abstract » | (added 2018-12-14)

  • Medicare Reimbursement Has Driven More PD

    Changes to the Medicare Prospective Payment System (PPS) in 2011 to create financial incentives for PD have worked, finds a new analysis of 6,433 dialysis clinics before and after the change. Since 2011, 6% more clinics offered PD, and program size increased from an average of 5.7 patients to 6.9. Non-urban, chain, and larger clinics were significantly more likely to have changed their PD practices in response to the PPS change.

    Read the abstract » | (added 2018-12-14)

  • Icodextrin Reduces PD Stroke Risk

    Stroke risk was compared in PD patients in Taiwan who did or did not use icodextrin. Icodextrin users had a lower risk and incidence of strokes than non-users.

    Read the abstract » | (added 2018-12-14)

  • Wanted: A Paradigm Shift from Urea to Sodium Removal

    When nephrology icon Zyblut Twardowski talks, we listen! When dialyzors in Seattle in the 1960s got 30 hours a week of dialysis, the mortality rate was 10%. Since then, short treatments—justified by the flawed NCDS study—were driven by the equally flawed notion of Kt/V urea.

    Read the abstract » | (added 2018-12-14)

  • Metaanalysis of PD for Kidney Failure due to PKD

    Polycystic kidneys may displace room for PD fluid, so can PD be a viable treatment option? A metaanalysis of 12 studies and more than 17,000 patients found…maybe. PD outcomes were about the same for those with PKD as with other primary kidney diseases, and some can do PD. More research is needed to determine who is suitable. Read the abstract.

    Read the abstract » | (added 2018-10-12)

  • PD and Dialysis Patient Employment

    In a Swedish study, 4,734 working-age (20-60 years old) patients who survived at least one year on in-center HD or PD were compared. Patients using PD had a 4% increased probability of employment over in-center HD—as well as a 6% lower disability pension and higher work income. Read the abstract

    Read the abstract » | (added 2018-10-12)

  • MXene Sorbents: A Step Toward a WAK

    A sorbent tested for use in a wearable artificial kidney was able to adsorb urea with 99% efficiency in testing—twice the level removed with standard dialysate. The hemocompatible sorbent did not damage cells or reduce cell viability at the concentrations tested. A successful sorbent product will facilitate the design of a WAK. Read the abstract.

    Read the abstract » | (added 2018-10-12)

  • Urgent Start PD + Diabetes

    A retrospective study compared the first 30-day outcomes and survival trends of 80 urgent start dialysis patients, 50 of whom (62.5%) did PD. Compared to those who started standard in-center HD, the dialysis-related complications were significantly lower for those on PD, and PD survival was higher as well. Read the abstract.

    Read the abstract » | (added 2018-10-12)

  • What Makes Home HD Patients Reach for On-Call Support?

    A 4-month prospective observational study analyzed the reasons why 58 home HD patients called the on-call nurse or technician. Most calls to nurses were made for clinical issues or machine set-up or alarm questions, some of which required a technician. Most of the technician calls were for machine malfunction, set-up and alarms, or water treatment. Read the abstract.

    Read the abstract » | (added 2018-10-12)