Journal Watch

  • Not even a little bit pregnant

    How much does waist size really grow on PD? Not much at all. A new study measured 44 PD'ers around the belly at hip and belly button height—full and empty. The average difference? About 3 cm or less—just about an inch and a quarter.

    Read the abstract » | (added 2011-02-24)

  • Survival on PD beats standard in-center HD hands down

    Studies done with data from the early 1990s found better survival on standard in-center HD than PD. But a new study pairing 6,337 PD patients who started treatment in 2003 with standard HD patients found just the opposite. Survival was significantly better with PD—especially for those under 65, and those who did not have heart disease or diabetes.

    Read the abstract » | (added 2011-02-24)

  • Extended catheters make PD possible for more people

    For those who can't have an abdominal PD catheter, an "extended" (i.e., presternal) catheter that can exit in the chest can make PD work. A new study found 1, 2, and 3-year catheter success rates that were slightly lower than standard PD catheters.

    Read the abstract » | (added 2011-02-24)

  • Icodextrin improved nutrition and inflammation in PD

    Replacing glucose-based PD fluid with icodextrin led to 66% better fluid removal, significantly higher protein levels, and significantly lower levels of the inflammation marker CRP.

    Read the abstract » | (added 2011-02-24)

  • Pain meds may one day protect the peritoneum

    COX-2 inhibitors fight pain and inflammation. A new study in mice has found that COX-2 drugs were able to reduce fibrosis and damage to the peritoneum caused by PD fluid. This finding may one day help people to do PD longer.

    Read the abstract » | (added 2011-02-24)

  • New resource for intraperitoneal drug delivery

    On PD, it's not hard to inject a drug into the PD bag so it goes into the peritoneum. Which drugs are safest and most effective this way? A new article tells you the scoop.

    Read the abstract » | (added 2011-02-24)

  • Hope for peritoneal fibrosis?

    Over time, the peritoneum can become fibrous and thickened, and less able to filter the blood during PD. A new study in rats suggests that erythropoietin (EPO) may help. Rats treated with EPO had less fibrosis. Down the road, perhaps this finding will help people.

    Read the abstract » | (added 2011-02-24)

  • Which is safer for placing a PD catheter: General or local anesthesia?

    Trick question. Turns out, they're both safe! In more than 300 people followed between 1999 and 2008, there were no major complications in either group. PD catheter failure rates were similar (5% for general, 7% for local).

    Read the abstract » | (added 2011-02-24)

  • Icodextrin PD fluid causes less weight gain

    We're not surprised to learn that PD fluid that doesn't contain dextrose (sugar) is less likely to cause weight gain! A study of 183 PD patients found weight gains after 3 years (88% of it fat) among those using standard fluid, and significantly less weight gain in an icodextrin group.

    Read the abstract » | (added 2011-02-24)

  • PD catheter placement: Surgeon or nephrologist?

    Does who places a PD catheter make a difference in complications or catheter survival? Not really, finds a new Greek study that looked at 152 patients who received 170 catheters. Only early leakage (easily treated) was more likely with nephrologist placement.

    Read the abstract » | (added 2011-02-24)