Journal Watch

  • Better sleep rhythms with nocturnal HD

    Who sleeps best on dialysis? A new study found the most normal levels of melatonin (a hormone that helps control sleep patterns) in people who did nocturnal HD. Those on PD also had better sleep than people who did standard in-center HD.

    Read the abstract » | (added 2011-02-24)

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  • 42% higher risk of death found with less-than-4-hour HD

    Short standard in-center HD treatments done 3 times a week were linked with a much higher risk of death in a new study of 8,552 people. Of course, "further studies are needed...."

    Read the abstract » | (added 2011-02-24)

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  • A Brazil nut a day keeps the doctor away

    Heart disease risk is higher among people on HD, due to oxidative stress (basically rust). Selenium reduces this stress—and Brazil nuts are the best known source. In a new study, 81 people on HD ate one Brazil nut each day. At the end of 3 months, their levels of the protective enzyme GSH-Px were normal.

    Read the abstract » | (added 2011-02-24)

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  • Nocturnal HD improves bone mineral levels

    Yes, we knew this—but this time, it's a randomized controlled trial of nocturnal (6 nights/week) vs. standard in-center HD (3 times/week). Compared to standard HD, those doing nocturnal had lower phosphorus—even without binders—lower PTH levels, and lower calcium-times-phosphorus products.

    Read the abstract » | (added 2011-02-24)

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  • On PD, higher uric acid levels predict faster loss of kidney function

    Keeping as much of your kidney function as you can is a plus on PD or HD. A new study from Korea has found that people on PD whose levels of uric acid were higher had a faster decline in their kidney function. Those with higher blood pressure tended to have higher uric acid levels.

    Read the abstract » | (added 2011-02-24)

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  • For lupus, HD may be a better option

    A small study of 36 women with lupus in Taiwan has found much better survival and less inflammation in those who did HD. Protein levels were higher on HD, too.

    Read the abstract » | (added 2011-02-24)

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  • Better nutrition with nocturnal HD

    A new study found better appetites, more energy, and higher protein intake in people doing 6 nights/week nocturnal HD. Even though they ate more foods high in phosphorus, their blood levels stayed good without binders. They were able to drink more fluids, too.

    Read the abstract » | (added 2011-02-24)

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  • PKD is not a barrier to successful PD

    In a study that compared 56 people with polycystic kidney disease on PD to 56 non-diabetic people with small kidneys on PD, there were no differences between the two groups after 37 months.

    Read the abstract » | (added 2011-02-24)

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  • Need an MRI? Ask for NAC + bicarb

    MRI contrast dye can damage kidneys. A new meta-analysis (study of studies) has found that two approaches are better than one in preventing this damage. N-acetylcystein (NAC, or Mucomyst®) plus bicarbonate-based IV fluid reduced the risk of damage by 35%. The authors say this combo treatment should be used for all high-risk patients—including those with CKD.

    Read the abstract » | (added 2011-02-24)

    Tags: Chronic kidney disease

  • CKD education saves lives

    A new study from Taiwan found that people who got CKD education were about 3 times less likely to need dialysis during the study period (about a year), and more than 5 times more likely to live than a control group that did not receive the education.

    Read the abstract » | (added 2011-02-24)

    Tags: Chronic kidney disease