Journal Watch
-
Glycated Albumin More Accurate in PD than Glycated Hemoglobin
Using hemoglobin A1c levels to assess glycemic control in people with diabetes using PD is risky, because anemia causes false negative results. In a 6-month study, 20 people with diabetes using HD were matched for age, sex, and post-meal glucose levels with people with diabetes using PD. In a multiple regression analysis, glycated albumin was the only independent predictor of plasma glucose levels.
Read the abstract » | (added 2016-05-12)
Tags: Hemodialysis
-
Some PD Patients at Risk for New Onset Diabetes
Among 612 people who did not have diabetes, 32 were diagnosed with the disease after starting PD. The risk of new diabetes was higher in those who were older, had higher BMIs, and whose blood had more markers of inflammation.
Read the abstract » | (added 2016-02-09)
Tags:
-
Why Do People Stop Doing Home HD?
Among 2,840 people who started home HD between 2007 and 2009, nearly one in four stopped within a year, while 1-year mortality was 7.6%. The risks of stopping home HD were higher among those with diabetes, and substance use (alcohol, tobacco, drugs). Those who were listed for transplant or lived in rural areas were less likely to stop home HD.
Read the abstract » | (added 2016-01-10)
Tags: Hemodialysis
-
Liraglutide Has Multiple Benefits in People with Diabetes on PD
In a small study, injectable liraglutide was tested in 16 people with type 2 diabetes who use PD, 11 of whom were previously on insulin, while three used oral medications and two controlled their blood sugar using diet alone. After 12 months, glucose fluctuations were reduced, post-meal blood sugars were lower, systolic blood pressure dropped—and left ventricular mass decreased (on echocardiogram).
Read the abstract » | (added 2015-12-10)
Tags:
-
What Predicts Transfer to Home HD After PD Failure?
In Australia and New Zealand, an analysis of all 10,710 patients treated with PD between 2000 and 2012 found that 2,915 transferred to HD—but just 156 started home HD. Among those who switched to home HD, more were male, obese, and had done PD longer. Older patients, those who stopped PD due to infection, who were underweight, whose ESRD was due to hypertension or diabetes, and those who were Aboriginal were less likely to go home.
Read the abstract » | (added 2015-11-11)
Tags:
-
Excessive Weight Gain in Year 1 of PD Predicts Poor Outcomes
In a PLoS One study, 148 incident PD patients were observed for a median of almost 2 years. Those who gained more than 3% of their body weight lost residual kidney function 4.17 times faster (p<0.001), and had higher blood pressure, more inflammation, and an increased rate of diabetes.
Read the abstract » | (added 2015-10-15)
Tags:
-
Icodextrin PD fluid reduces insulin resistance in non-diabetic patients
Even without diabetes, insulin resistance can add to cardiovascular disease risk in people with CKD. A new study randomized non-diabetic adults to APD with 2.5% glucose (n=27) for the long dwell or icodextrin 7.5% (n=33). At 90 days, the icodextrin group had lower levels of insulin resistance.
Read the abstract » | (added 2015-07-08)
Tags:
-
Glucose challenge test (GCT) detects glucose metabolism disorders in PD
When glucose-based PD fluid is used, it can be a challenge to see if there are blood sugar issues. In 20 people on PD who did not have a history of diabetes, an initial GCT detected impaired glucose tolerance in eleven and diabetes mellitus in four. About 2 years later, twelve patients had glucose metabolism disorders—but none had diabetes.
Read the abstract » | (added 2015-05-09)
Tags:
-
More reasons to use PD fluid with less sugar
Using a novel index created by dividing the glucose content of PD solution by body weight, this study looked at the impact of PD fluid sugar on hemoglobin A1c, fluid overload, and inflammation (measured by interleukin (IL) 6) in 43 people on PD. Higher sugar levels were linked with worse diabetes control, more fluid overload, and higher IL-6 levels.
Read the abstract » | (added 2015-03-11)
Tags:
-
Don’t trust glucometers on people using PD with icodextrin
Glucometer test strips can’t distinguish glucose from other sugars, like maltose. When icodextrin is used for PD in people with diabetes, standard glucometer use is risky. Blood glucose test results from glucometers can’t be trusted, and people may be given insulin they don’t need (which could cause coma or death). Three case reports show why this is the case—and the authors suggest using glucose-specific blood tests instead.
Read the abstract » | (added 2014-12-09)
Tags: