Journal Watch
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Evaluating Patterns and Outcomes in the Prescription of Incremental Peritoneal Dialysis in Support of Shared Decision-Making
This study of 527 patients from 2012-2023 found that incremental PD was safe to prescribe. They found patients were still on their incremental PD prescription at one year (64%) and two years (36%). Those more likely to increment sooner were younger, male, and had lower albumin. Younger patients with diabetes were more likely to switch to HD. Mortality rates were low at .11 events/person year. A clinical score for shared decision-making and treatment expectations was constructed and tested, but needs validation.
Read the abstract » | (added 2026-09-18)
Tags: Incremental PD, Shared Decision making, Treatment Expectations
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Hemodiafiltration versus High-flux Hemodialysis and Risk of Mortality: A Multinational Target Trial Emulation
A Fresenius study of almost 20,000 patients in eight European countries from 2014-2019 found that hemodiafiltration (HDF) reduced all-cause mortality risk by 28% over conventional high flux HD. Even better, all-cause mortality was reduced 33% with high volume (23 liters per session) HDF compared with conventional high flux HD.
Read the abstract » | (added 2026-09-18)
Tags: Hemodiafiltration, HDF, All cause Mortality
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Backup AVFs in PD
A small (n=115) retrospective cohort study compared PD patients with and without a backup AVF (bAVF). There were no differences in mortality or transfer to HD between groups, but having a bAVF was linked with a lower HD transfer risk with a CVC. Complications were similar.
Read the abstract » | (added 2026-06-17)
Tags: Backup AVF, BAVF, Mortality, CVC, Transfer To HD
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PD Comparable to HD for Patients with AKI
The choice of kidney replacement therapy (KRT) for AKI requiring dialysis is a modifiable factor that can impact outcomes. The comparative effectiveness of PD vs. HD in AKI is controversial. A systematic review and meta-analysis of seven studies compared mortality outcomes, recovery of kidney function, and infectious complications between PD and HD in patients with AKI. No significant mortality differences were found and kidney function recovery was similar between groups, though PD led to a significantly shorter time to kidney function recovery. Infection rates were also similar.
Read the abstract » | (added 2026-05-15)
Tags: Kidney Replacement Therapy, KRT, PD, AKI
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Women May Fare Better on PD Than Men
The International observational PDOPPS has turned its attention to the examination of sex differences in PD outcomes like mortality, transfer to HD, peritonitis, and transplant rates. PD patients from eight countries (n=25,292) were 43% female on average, and females had lower mortality rates, fewer transfers to HD, and lower rates of peritonitis. In South Korea, for example, median time on PD was 6.4 years for females, but just 4.9 years for males.
Read the abstract » | (added 2025-12-17)
Tags: PDOPPS, Gender, PD Outcomes, Mortality, Transfer To HD, Peritonitis, Transplant Rates
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PDOPPS on Incremental PD Starts and Clinical Outcomes
What dose should be offered at the start of incremental PD? An international prospective cohort study assessed 1,365 patients from 128 clinics in seven countries who began standard (63%) or incremental (37%) PD within3 months of January 1, 2014 until December 31, 2017. There was no significant difference in transfer to HD between the standard PD (15%/year) and incremental PD (14%/year), nor were there differences between groups in peritonitis or mortality.
Read the abstract » | (added 2025-11-11)
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Body Mass Index and PD: A Meta-analysis
Analysis of adjusted data from 18 studies found that underweight PD patients had a significantly higher risk of mortality than those with normal BMI, though obesity did not. However, obese PD patients had a significant increase in the risk of peritonitis. Neither underweight nor obesity increased the risk of technique failure or transfer to HD.
Read the abstract » | (added 2025-11-11)
Tags: Body Mass Index, PD, Meta analysis
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Impact of Embedded PD Catheters on Peritonitis and Mortality
Moncrief and Popovich pioneered a buried PD catheter technique (inexplicably abbreviated as SMAP). In a study, outcomes of 285 consecutive patients who had PD catheters implanted either directly (n=96) or via SMAP (n=189) were analyzed retrospectively. Both the risks of peritonitis and mortality were significantly lower in the SMAP group.
Read the abstract » | (added 2025-07-16)
Tags: Embedded PD Catheters, Peritonitis, Mortality, Moncrief And Popovich Technique
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U.S. PD Outcome Trends: 2009 to 2018
A USRDS analysis of data from 101,640 incident PD patients found a decrease in overall mortality from 11% (2009) to 8.4% (2018). The probability of switching to in-center HD a year after PD initiation also dropped by about 2% in patients under 75 years old.
Read the abstract » | (added 2025-07-16)
Tags: Chronic Dialysis, Incident PD , Mortality, Peritoneal Dialysis, Clinical Epidemiology
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Urgent-start HD (USHD) vs. Urgent-start PD (USPD): A Meta-analysis
Compiled data from seven studies and 1,338 patients found significantly fewer complications (infectious and noninfectious) and mortality with USPD than with USHD. The authors concluded that USPD patients “could potentially function as an appropriate replacement for USHD.”
Read the abstract » | (added 2025-07-16)
Tags: Urgent start HD, Urgent start PD