Journal Watch
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Longer Survival with Extended Home HD
A study in Turkey compared 348 patients doing extended home HD (418 minutes) matched with 1,047 doing standard in-center HD (242 minutes) and followed both groups for about 55 months. The extended home HD patients had an all-cause mortality rate of 3.76 per 100 patient years—vs. 6.27 for the in-center HD patients; a significant 40% reduction.
Read the abstract » | (added 2023-10-13)
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Incremental PD and Patient Outcomes: Registry Data
Between 2007 and 2017, incremental PD use increased by 2.7% in the ANZDATA database. Most (67%) used the approach for one year or less. After controlling for patient and center variables, starting PD with incremental treatments reduced peritonitis risk and transfers to in-center HD, with no increase in mortality.
Read the abstract » | (added 2023-09-13)
Tags: Incremental PD, Incremental Treatments, Peritonitis, Mortality Rate
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Incremental PD and Quality of Life
In a 4-year study (2015-2019) of adults starting PD and followed for one year, those who used incremental PD had better KDQOL physical composite, burden of kidney disease, and effects of kidney disease scores, as well as less hospitalization and lower mortality rates (non-significant).
Read the abstract » | (added 2023-09-13)
Tags: Incremental PD, KDQOL, Mortality Rate, Quality Of Life
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Systemic Immune-Inflammation Index (SII) and Mortality on PD
Among 1,419 PD patients from 2007 to 2019, SII was calculated as platelet count x neutrophil count/lymphocyte count. During a median 42 month follow up, 321 patients died, 171 of cardiovascular disease. Each 1 standard deviation increase in the SII was associated with a 20.2% rise in all-cause mortality and 28% in cardiovascular-specific mortality.
Read the abstract » | (added 2023-09-13)
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Early Survival Advantage for Incremental PD
From 2008 to 2017, 1,315 patients from one hospital who started PD were enrolled in a study that propensity matched them 1 (incremental; n=285):2 (full dose; n=502) for age, sex, residual kidney function and urine volume, hemoglobin, serum albumin, and other variables. For the first 6 years, intermittent PD had significantly better survival than full dose PD, with a 39% lower risk of all-cause mortality and 41% less cardiovascular mortality. This advantage disappeared with longer time on PD.
Read the abstract » | (added 2023-09-13)
Tags: Intermittent PD, Full Dose PD, Mortality
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Meta-analysis of PD Remote Patient Monitoring
Analysis of data from 22 studies revealed that remote monitoring for PD reduced technique failure, hospitalization, and mortality vs. traditional PD monitoring.
Read the abstract » | (added 2023-04-19)
Tags: Remote Monitoring, PD, Technique Failure, Hospitalization, Mortality, Traditional PD Monitoring
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Serum Phosphorus and Survival on PD
Data from 5,847 PD patients between 2014-2017 from seven countries in the PDOPPS study found that compared to an optimal range of 3.5-4.5mg/dL, the hazard ratio (HR) for all-cause mortality was 19% higher when phosphorus was 5.5-6.5 and 53% higher when phosphorus was greater than 6.5. When 6 months of data were examined, the linkage was even stronger.
Read the abstract » | (added 2023-02-13)
Tags: PD, Serum Phosphorus, PDOPPS, Hazard Ratio, All cause Mortality
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Cycler vs. Manual PD for Survival
A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.
Read the abstract » | (added 2022-12-19)
Tags: Peritoneal Dialysis, PD, Modality, Automated Peritoneal Dialysis, APD, Continuous Ambulatory Peritoneal Dialysis, CAPD, All cause Mortality, ACM, PD Failure, Survival
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The Predictive Value of Early, Non-infectious PD Complications
A prospective, multicenter cohort study of 1,596 people starting PD in New Zealand from 2014 to 2018 (inclusive) looked at survival and time on PD of those who had catheter-related exit site dialysate leaks or other leaks within 30 days of PD start. Peritonitis-free survival, first PD catheter survival, and tunnel infection free survival were secondary outcomes. Among the 102 with an early complication, overall mortality, the rate of stopping PD, and first catheter failure were all higher.
Read the abstract » | (added 2022-11-16)
Tags: PD, Survival, Peritonitis free Survival, First PD Catheter Survival, Tunnel Infection Free Survival, Early Catheter related Complication
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Better COVID Survival with PD and Home HD
Among 1,336 people whose kidneys failed between March, 2020 and January, 2021, 13.12% (n=178) contracted COVID-19. Of these, most (n=139) did standard in-center HD, and 33 (3.87%) died. On PD, 39 people developed COVID, and 1 (0.81%) died. On home HD, there were zero cases of COVID and no deaths. Five transplant patients developed COVID, with a mortality rate of 1.47%.
Read the abstract » | (added 2022-10-17)
Tags: Covid, Standard In center HD, PD, Mortality, Home HD, Home Hd And Covid, Transplant