Journal Watch - 2016

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  1. Milk Thistle Extract Improved Hemoglobin and Albumin in PD

    Silymarin is an antioxidant. Among 50 people on PD randomly assigned to take silymarin (n=28) or a control (n=22) for 2 months, those who took the supplement three times a day had significantly higher antioxidant levels. They also had significant increases in hemoglobin and albumin levels at the p<0.05 level. (NOTE: Always inform a nephrologist of any supplement use.)

    Read the abstract » | (added 04/12/2016)

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  2. PD Catheter Placement: Does Timing Matter?

    Do patients who are able to wait 14 days before using a PD catheter have less peritonitis than those who use it sooner? Can they do PD longer? Do they live longer? There were no significant differences in any of these parameters, finds a new observational study of 149 patients, 80 early and 69 delayed. (NOTE: This is good news for early start PD.)

    Read the abstract » | (added 04/12/2016)

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  3. Survival on PD is Better with Normal Magnesium Levels

    A retrospective study of 253 incident PD patients followed for up to 10 years found that deaths due to cardiovascular causes (58.3%) were linked with low serum magnesium levels. Low serum albumin, and levels of triglycerides, potassium, calcium, and phosphate were also important. Those in the group with the lowest magnesium had significantly higher all-cause mortality (p<0.001).

    Read the abstract » | (added 04/12/2016)

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  4. Kidney to Kidney: 2008K@Home and NxStage System One

    Among home HD patients followed for a year, there were a few differences between users of the 2008K@Home and the NxStage System One. 2008K@Home users did not do treatments as often—but their mean standardized Kt/Vs were significantly higher (2.75 vs. 1.99). System One users tended to use less EPO. Other outcomes and lab test values were largely similar.

    Read the abstract » | (added 03/10/2016)

    Tags: Hemodialysis

  5. Update on Implantable and Bioengineered Kidneys

    A new review focuses on two implantable innovations that may reduce the need for dialysis. An artificial kidney is a biohybrid system that will mimic renal structure and function. A bioengineered kidney will be based on native kidneys.

    Read the abstract » | (added 03/10/2016)

    Tags: Hemodialysis

  6. Sleep Problems With Automated PD

    Compared to people with stage 3b-5 CKD (n=89), those using a cycler for PD (n=22) had about the same, higher level of sleep problems as those on standard HD (n=75). In-home sleep measures and surveys found low levels of oxygen during sleep, and disrupted sleep cycles.

    Read the abstract » | (added 03/10/2016)

    Tags: Hemodialysis

  7. CKD Case Management Boosts PD Use

    A Fresenius program of renal care coordinators (RCCs) in late-stage CKD helped ease the transition onto dialysis. Compared to non-participants (693), the 738 patients with RCC case managers were more likely to start PD or have a permanent vascular access for HD, and have a serum albumin level >4.0g/dL.

    Read the abstract » | (added 03/10/2016)

    Tags: Hemodialysis

  8. PD First Comes to Brazil

    Since 2014, researchers in Brazil have made urgent-start PD an option for patients with little advance warning of kidney failure. After catheter placement, patients did in-center, alternate-day, intermittent PD until training could be done. Among 35 patients, survival was 80% and technique survival was 85.7%. The chronic PD program grew by 41.1%.

    Read the abstract » | (added 03/10/2016)

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  9. ISPD Releases Free PD Teaching Syllabus

    The Nursing Liaison Committee of the International Society for Peritoneal Dialysis (ISPD) has reviewed PD training programs from around the world. An expert group has developed a consensus document to help PD nurses train patients and care partners. The free curriculum is flexible, based on adult learning principles, and includes checklists.

    Read the abstract » | (added 03/10/2016)

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  10. Metaanalysis: Better PD Catheter Outcomes Via Laparoscope

    An analysis of five randomized trials and 11 cohort studies compared laparoscopic PD catheter placement to surgery. The laparoscopic approach had less catheter migration and the catheters lasted longer, though there was a slightly higher risk of bleeding.

    Read the abstract » | (added 03/10/2016)

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