Rat study: Celexicob reduces peritoneal fibrosis

COX-2 is involved in fibrosis and the growth of new blood vessels. Is there a way to protect the peritoneal membrane using a COX-2 inhibitor so it lasts longer for PD? Perhaps one day there will be. A new study found that rats given a substance that causes fibrosis had fewer new blood vessels and milky spots, and far less fibrosis than controls.

Read the abstract » | (added 2011-02-24)

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Mupirocin (Bactroban®) reduces staph exit site infection and peritonitis in PD

A meta-analysis of 14 studies looking at 1233 patients and 1217 controls has concluded that using an ointment with mupiricin can help prevent PD problems. Exit site infections and peritonitis—both due to staph aureus and to some other germs—were reduced by as much as 72%.

Read the abstract » | (added 2011-02-24)

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PD catheter placement: Surgeon or nephrologist?

Does who places a PD catheter make a difference in complications or catheter survival? Not really, finds a new Greek study that looked at 152 patients who received 170 catheters. Only early leakage (easily treated) was more likely with nephrologist placement.

Read the abstract » | (added 2011-02-24)

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Icodextrin PD fluid causes less weight gain

We're not surprised to learn that PD fluid that doesn't contain dextrose (sugar) is less likely to cause weight gain! A study of 183 PD patients found weight gains after 3 years (88% of it fat) among those using standard fluid, and significantly less weight gain in an icodextrin group.

Read the abstract » | (added 2011-02-24)

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