Journal Watch
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Early PD survival benefit comes from avoiding HD catheters
Studies have found better survival on PD than standard HD in the first 1-2 years of treatment. A new study of 40,526 people found that the main reason for this difference is that those on PD did not use central venous HD catheters.
Read the abstract » | (added 2011-06-21)
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PD with PKD: Yes, it's possible
A Chinese study matched 42 people with and 84 without PKD as they started PD. After 5 years, survival in both groups was the same. There was no difference in the rate of peritonitis, though the PKD group was more likely to get hernias.
Read the abstract » | (added 2011-06-21)
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Pilot results of a wearable artificial kidney
Eight people on HD have now tested a new wearable HD device for 4-8 hours. Fluid was removed with no heart problems, and some wastes were removed as well. The safety devices for needle disconnection and clotting worked quickly. A step forward!
Read the abstract » | (added 2011-06-21)
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Risk factors linked to renal cell cancer (RCC) after long-term dialysis
RCC occurs at higher rates in those who have been on dialysis for many years. If you know the risk factors, you can ask for screening. Those at highest risk in a large study were men; older people; ESRD caused by an obstruction, FSGS, or tuberous sclerosis; and those whose kidneys grew new cysts.
Read the abstract » | (added 2011-06-21)
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Statin use may boost PD survival
A new study from Korea has found that taking a statin drug to lower cholesterol helped people on PD live longer—whether or not they had diabetes. The researchers suggest that larger, randomized studies are now needed.
Read the abstract » | (added 2011-06-21)
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NAC protects PD membrane from sugar damage in rats
Over time, caramelized sugars in PD fluid can scar the peritoneal membrane to the point where PD may no longer work. In a rat study, an antioxidant (N-acetylcysteine, or NAC) reduced this damage. NAC may one day prove to be a treatment for humans.
Read the abstract » | (added 2011-06-21)
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Bone loss in women on dialysis—the role of estrogen
A study of 112 postmenopausal women on HD in Japan found that estrogen was closely linked to bone density. The authors conclude that taking estrogen may help prevent bone loss throughout life in women on HD.
Read the abstract » | (added 2011-05-23)
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A prospective study of 4 vs. 8 hours of HD in-center 3 times a week
Which is better, standard HD or more HD? A new study matched 247 people who agreed to try nocturnal in-center HD with people on standard HD. A year later, survival rates were 3.5 times higher (and hospital stays were lower) with more HD. Heart health and cognitive function were far better with more HD, too, while quality of life dropped in the standard HD group. (Now, why are we NOT surprised?)
Read the abstract » | (added 2011-05-23)
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Cycler PD has better outcomes than manual PD for those under age 65
Among 282 people on PD, younger people were much more likely to keep doing PD—and much more likely to survive—if they used a cycler.
Read the abstract » | (added 2011-05-23)
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New model using routine lab tests can predict progression to kidney failure
Researchers looked at data from a total of 8,391 people with stages 3–5 CKD to see if lab test results could predict who would progress to end-stage. A model that included age, sex, GFR, and protein in the urine worked best.
Read the abstract » | (added 2011-05-23)
Tags: Chronic kidney disease