Journal Watch
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Adsorptive column removes B2m
Too-high levels of B2m cause amyloidosis in people on dialysis, with joint and bone pain. In Japan, people dialyzed using the Lixelle S-15 adsorptive column had significantly less B2m in their blood after a year of 3x/week treatments. They were also stronger and had less joint pain.
Read the abstract » | (added 2011-11-28)
Tags: Chronic kidney disease
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Urgent-start PD is feasible with a plan
In this small study, 9 people who had an urgent start for PD were compared to 9 people who started PD with more time. A standard protocol was written to support urgent start PD. After 90 days, both groups were doing equally well.
Read the abstract » | (added 2011-11-28)
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Alternate-night HD improves bone minerals & blood pressure
Among 63 people in Australia who switched from standard HD to alternate-night HD, bone mineral balance and blood pressure improved after 18–24 months. Left ventricular mass did not improve, but remained stable.
Read the abstract » | (added 2011-11-28)
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Protein intake improves after a switch from standard to nocturnal HD
After 8 months of nocturnal HD, 15 people who switched from standard in-center HD had significantly higher protein intake. Their phosphate intake rose as well—but their serum phosphate levels did not, even without binders.
Read the abstract » | (added 2011-11-28)
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Antioxidant improves residual kidney function in PD
Four weeks of twice-daily oral N-acetylcysteine, an antioxidant, significantly increased residual kidney function of people on PD in a small study (n=10).
Read the abstract » | (added 2011-10-27)
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Home dialysis boosts patient employment in Finland
A new study looked at employment results among 2,637 people ages 15 to 64 on dialysis or with kidney transplants in Finland. While just 19% of those on standard in-center HD were working, 39% of those on home HD, 40% of those with working transplants, and 44% on cycler PD were employed.
Read the abstract » | (added 2011-10-27)
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Implantable artificial kidney—progress
Three key bits of technology are needed to make an implantable artificial kidney possible: high efficiency membranes to remove water, a way to keep blood from clotting, and a way to mimic the selective action of kidney cells for removing wastes. Progress is occurring in each area.
Read the abstract » | (added 2011-10-27)
Tags: Chronic kidney disease
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Basing dialysis dose on REAL toxins
Dialysis "adequacy" is based on removing urea—a waste that is not all that toxic. A new article points out that finding and choosing wastes that truly are toxic could change the way we measure dialysis for the better.
Read the abstract » | (added 2011-09-29)
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Using L-carnitine instead of sugar for PD fluid
Over time, sugar can harm the peritoneal membrane so it can't be used for PD. L-carnitine is a substance the body needs for energy. In a new rat study, PD fluid with L-carnitine removed as much—or more—water and wastes as sugar-based fluid. The new fluid was well tolerated and did not damage the peritoneum.
Read the abstract » | (added 2011-09-29)
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PD as a treatment for severe heart failure
In a small study, people whose CKD had not yet caused kidney failure were helped by peritoneal dialysis. After 2 months, the 19 study participants lost water weight, breathed easier, could sleep lying flat, and had no hospital stays for fluid overload.
Read the abstract » | (added 2011-09-29)
Tags: Chronic kidney disease