Journal Watch
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Implantable microdialysis without dialysate fluid – in rats
What if we could implant an artificial kidney that did not require dialysate fluid? Researchers have developed a microdialysis system using microfluidic channels and nanoporous membranes, and tested it in rats with kidney failure. Filtrate was successfully collected with no blood leaks in the system, and the levels of creatinine in their blood was significantly reduced.
Read the abstract » | (added 2015-07-08)
Tags: Dialysis
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More glucose in PD fluid makes it harder to cure peritonitis
A look back at bacterial peritonitis among 187 people on CAPD compared those whose peritoneum was exposed to more than 140 grams per day of glucose—or less. Those who used less glucose had a higher cure rate, fewer relapses, and less need for catheter removal.
Read the abstract » | (added 2015-07-08)
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PKD liver and kidney size may limit PD
In Japan, oversized polycystic kidneys may be treated with transcatheter arterial embolization (TAE) to cut off their blood supply and shrink them. Among two small groups of people with PKD, even those with reduced kidney volume still tended to develop hernias.
Read the abstract » | (added 2015-06-10)
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Progress toward reengineering catheters to reduce infection
Can we eliminate exit site infections by redesigning catheters? Bioengineers are working on a way to create a biological seal that would keep germs out. A new device being tested uses a removable protective membrane that slowly grows out of the body, leaving a dry groove that reduces infections—at least in goats.
Read the abstract » | (added 2015-06-10)
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Metaanalysis of best practices in pregnancy on dialysis
What works best to ensure a healthy baby if women on dialysis become pregnant? A systematic literature analysis found that long-hour HD has the most support, while correcting vitamin B12, folate, iron, anemia, vitamin D, and calcium levels is also important. Success rates of greater than 75% are possible.
Read the abstract » | (added 2015-06-10)
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Status Report: Home HD in Japan
While just 0.1% of all Japanese people on dialysis use home HD, this number has been growing quickly. Work groups of the Japanese Society for Home Hemodialysis have been set up to start a patient registry and advise on supply and wastes and the cost burden for those who self-pay. Further challenges will include recruitment, education, a business model, and more.
Read the abstract » | (added 2015-06-10)
Tags: Home dialysis
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New self-cannulation aid: Tattoo dots
In a case report of a patient who had a hard-to-feel fistula, small dots were tattooed to guide cannulation. With the permanent dots in place, the individual was able to self-cannulate and do home hemodialysis successfully.
Read the abstract » | (added 2015-06-10)
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Home hemodialysis needs you! Special Kidney International supplement.
A special supplement of Kidney International focuses on how to implement home hemodialysis, from policies and procedures to equipment, recruitment, safety, prescription, staffing, and more—from global experts. Don't miss it!
Read the abstract » | (added 2015-05-09)
Tags: Home dialysis
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Dosage of Tamiflu® for people on PD
A new study finds that a single, 75mg dose of oseltamivir may be enough for people on PD who don’t have residual kidney function. The more residual function people had, the more efficiently the drug was removed—so more was needed for an optimal response.
Read the abstract » | (added 2015-05-09)
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Gene therapy via nanoparticles reduces peritoneal fibrosis in mice
Gene therapies may reduce peritoneal fibrosis—a leading cause of PD failure. Delivering transforming growth factor using nanoparticles worked in a mouse study.
Read the abstract » | (added 2015-05-09)
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