Journal Watch
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Are infections requiring hospitalization more common with PD or standard HD?
A study in Canada paired 910 people on PD with people on HD, matched by age, race, smoking, BMI, comorbid conditions, and lab data. After 2 years, researchers found that those on PD were more likely to be in the hospital for peritonitis—but less likely to have sepsis or pneumonia than those on standard HD.
Read the abstract » | (added 2012-09-25)
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Reasons why patients prefer more HD
An in-depth, interview study of 10 short daily or nocturnal HD patients in Canada found four main reasons why they liked their choice. 1) They felt better physically and mentally. 2) They felt more in control of their time. 3) They didn't feel "sick" and were more able to work. 4) They had the support they needed to succeed.
Read the abstract » | (added 2012-09-25)
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PD in older patients
This study from Ireland looked at 148 people over age 50 who started PD between 1998 and 2008. The mean age was 63; most were over 70. The researchers found no difference in survival or technique survival by age, though older people did need a longer hospital stay to get started on PD.
Read the abstract » | (added 2012-08-16)
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Short daily HD reduces left ventricular mass
The Frequent Hemodialysis Network trials found significant reductions in left ventricular mass (LVM)—with greater benefit for patients whose left ventricular mass was higher than normal at the start of the study.
Read the abstract » | (added 2012-08-16)
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Short daily HD survival 13% better than than standard in-center HD
When 1,873 short daily home HD patients were matched with 9,365 standard in-center HD patients, those who did more frequent HD had a better chance of living longer.
Read the abstract » | (added 2012-08-16)
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Metaanalysis: More HD boosts heart health
A metaanalysis of 46 studies concluded that switching from standard in-center HD to longer and/or more frequent HD significantly reduced left ventricular mass and improved blood pressure and the cardiac ejection fraction.
Read the abstract » | (added 2012-08-16)
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Intensive HD survival 50% better than standard in-center HD
A new study comparing 420 patients in the International Quotidian Dialysis Registry with 338 matched standard in-center HD patients from the DOPPS study found that only 13% of patients who did at least 5.5 hours of HD at least three times a week died—vs. 21% who did standard treatments.
Read the abstract » | (added 2012-08-16)
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Metaanalysis: Later dialysis start is better for HD
Starting dialysis at a lower GFR allows more time for access placement and options education. But the U.S. trend has been to start earlier. A new metaanalysis of 17 studies found that starting dialysis at a higher GFR was linked with a significantly higher risk of all-cause mortality—in HD, but not PD. The mortality risk was lower when GFR was calculated than when it was estimated.
Read the abstract » | (added 2012-08-16)
Tags: Chronic kidney disease
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Mupirocin best for preventing PD exit site infections
A new double blind, controlled study of mupirocin antibiotic ointment vs. polysporin found that mupirocin came out on top. Twice as many patients who used polysporin had exit site redness and they were more likely to get fungal infections.
Read the abstract » | (added 2012-08-16)
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How to do urgent-start PD
Researchers developed an urgent-start PD plan to address the needs of people who needed dialysis right away and had not chosen a treatment option. The outcomes of urgent-start PD patients were very similar to those of regular-start patients, though the urgent-start group had more minor leaks.
Read the abstract » | (added 2012-08-16)
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