Risk of Left Ventricular Hypertrophy Tied to Fluid Overload on PD

A single hospital had 226 enrolled PD patients between late 2018 and January 2021. Using bioimpedance analysis and cardiac color Doppler ultrasound, patients were divided into an LVF and a non-LVF group, and into a normal volume and overhydration group. Of participants, 125 (55.3%) had LVH. Overhydration and low hemoglobin levels were independent risk factors for LVH.

Read the abstract » | (added 2022-06-10)

Tags: PD, LVH, Overhydration, Volume Loads

Cardiovascular Benefits of Benefits

A review considers the impact of nocturnal HD on cardiac remodeling, myocardial stunning, hypertension, heart rate variability, sleep apnea, coronary calcification, and endothelial dysfunction.

Read the abstract » | (added 2020-04-13)

Tags: Benefits, Cardiovascular, Home Hemodialysis, Myocardial Stunning, Nocturnal Hemodialysis, Vascular Calcification, Cardiovascular Disease

PD vs. In-center HD for Sudden Cardiac Death

A Korean registry study of 132,083 PD and in-center HD patients followed between 1985 and 2017 analyzed 34,532 deaths. Sudden cardiac death (SCD) was responsible for 19.6% of deaths on PD and 22.2% of deaths on in-center HD. Even after adjusting for age and comorbidities, the risk of SCD was higher with HD.

Read the abstract » | (added 2020-01-09)

Tags: PD, In center HD, Sudden Cardiac Death

Sudden Cardiac Death (SCD) in PD vs. HD

A Korean registry analysis of 132,083 dialysis patients between 1985 and 2017 found that SCD caused 19.6% of the 34,632 deaths. Even after adjusting for age and significant comorbidities, HD was independently associated with SCD, as was diabetes.

Read the abstract » | (added 2019-10-14)

Tags: SCD, Sudden Cardiac Death, PD, HD

Peritonitis Predicts Long-term Cardiac Outcomes on PD

A large study (n=5,707) of PD patients from Brazil has found that just one bout of peritonitis boosts the risk of late cardiovascular death by 22%. Two bouts of peritonitis raised the risk by 78%, three by 181%, and four by 284%.

Read the abstract » | (added 2017-01-09)

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Nocturnal HD may reduce risk factors for sudden heart death

Sudden cardiac death is the leading cause of death on dialysis. A chart review study with ECGs has found that a year of nocturnal HD significantly improved heart function vs. standard in-center HD, even before changes to the left ventricle could be seen. More frequent nocturnal HD decreased Tpeak to Tend and QRS amplitude variation.

Read the abstract » | (added 2014-01-08)

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Why nocturnal HD reduces sudden cardiac death

Prolonged QTc intervals between heartbeats increases the rate of sudden cardiac death in people whose kidneys work. In an ECG study, patients who did nocturnal HD had shorter QTc intervals—even if those intervals were long before dialysis and even before changes to the left ventricle.

Read the abstract » | (added 2013-08-22)

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Metaanalysis: More HD boosts heart health

A metaanalysis of 46 studies concluded that switching from standard in-center HD to longer and/or more frequent HD significantly reduced left ventricular mass and improved blood pressure and the cardiac ejection fraction.

Read the abstract » | (added 2012-08-16)

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Normalizing "unphysiology" with longer and/or more frequent HD

Studies of intensified HD regimens have found superior results to standard in-center HD, including better cardiac outcomes. This review article surveys the evidence that supports the hypothesis that more physiologic dialysis leads to better outcomes.

Read the abstract » | (added 2011-12-22)

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More frequent HD linked with less cardiac stunning

During standard HD, the heart gets less blood, which causes damage called "stunning." In a study of 46 people on standard, short daily, or nocturnal HD, those whose treatments were done more often had less cardiac stunning. Those on nocturnal had the least.

Read the abstract » | (added 2011-06-21)

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