Journal Watch
High Peritoneal Transport and Long-term PD Outcomes
Among 470 patients who did PD for up to 10 years in Hong Kong, the peritoneal transport rate was able to differentiate survivors. After the first few years of PD, having high peritoneal transport became a significant risk factor for mortality.
Read the abstract » | (added 2018-05-11)
APD Remote Monitoring Boosts Patient Independence
An observation study of 37 automated PD patients followed by remote monitoring found that prescriptions were modified more often than when monitoring was not done—personalizing treatments better to patients’ needs—and fewer emergency visits were needed, for more efficient use of healthcare resources.
Read the abstract » | (added 2018-05-11)
Tags: Automated Peritoneal Dialysis, Remote Monitoring, Patient Independence, Prescription Of Dialysis
Albumin Predicts Survival in Anuric PD Patients
Patients who don’t make urine have a better chance of survival on PD if their serum albumin levels are 3.6 g/dL or higher, finds a new study of 505 PD patients in Korea. Age, diabetes, ultrafiltration volume, and serum creatinine levels were other factors.
Read the abstract » | (added 2018-05-11)
Is the Future Near? Portable Dialysis and Implantable Devices
Portable and wearable PD and HD devices are in development that have the potential to improve patient mobility and autonomy, and perhaps increase technique survival. Bioartificial kidneys that may partly replace some of the endocrine functions of kidneys are on a longer development horizon, followed by miniaturized, implantable devices. Multiple challenges must be overcome for any of these options to become available.
Read the abstract » | (added 2018-05-11)
Tags: Bioartificial Kidney, Implantable Artificial Kidney, Renal Replacement Therapy, Wearable Artificial Kidney
HD at Home—Review of Current Machines
A new review articles compares and contrasts home HD machine options.
Read the abstract » | (added 2018-05-11)
Head to Head: 8-hour Hemodialysis vs. 4-hour Hemodiafiltration
A randomized trial assigned 12 nocturnal HD patients to either two weeks of 8-hour HD or 4-hour HDF, followed by a crossover to the other option. Participants were also randomized to one of two dialyzers: a Fresenius FX80 or a Nipro Elisio. The 8-hour HD treatments removed significantly more urea and creatinine. But, the HDF removed more FGF23—and several other toxin levels were the same. The FX80 dialyzer cleared somewhat more B2M.
Read the abstract » | (added 2018-05-11)
Tags: Nocturnal HD, Extended hours Haemodialysis, Haemodiafiltration
35-year Patient Survival on Home HD
A case study reports on the 35-year survival of a man with Alport’s syndrome who uses thrice-weekly conventional home HD—and still works 6-8 hours per day at age 65—despite no residual kidney function.
Read the abstract » | (added 2018-05-11)
Emergent Start PD Yet Again
Learn about the rationale and feasibility of using PD as a first dialysis option for emergent start patients instead of inserting a central venous catheter and starting HD. .
Read the abstract » | (added 2018-04-12)
Tags: End stage Renal Disease, Haemodialysis, Peritoneal Dialysis, Unplanned Start, Urgent Start
LVH Regression in the FHN Trials
Among the 243 randomized patients with biomarker data in the daily HD trial, 121 had no change, 77 got better, and 45 got worse over the course of the study. Changes in levels of collagen turnover and klotho enzyme levels seemed to predict which patients would improve; a finding that will need to be verified in another study.
Read the abstract » | (added 2018-04-12)
Tags: Copeptin, Brain Natriuretic Peptide, Cardiac Biomarkers, Frequent Hemodialysis, Klotho, Left Ventricular Hypertrophy, Markers Of Collagen Turnover
Low Molecular Weight Heparin as Anticoagulation for Nocturnal HD
How can the dialysis circuit be kept free of clots during slow, HD treatments done during sleep? In a small study, 12 patients who did alternate night, 8-hour treatments were randomized to nadroparin (a low molecular weight heparin) or unfractionated heparin. The dosing regimens were adapted to make them more practical for overnight use. Both were effective, but with different monitoring requirements.
Read the abstract » | (added 2018-04-12)
Tags: Anticoagulation, Home Haemodialysis, Low molecular Weight Heparin, Nadroparin, Unfractionated Heparin