Journal Watch

  • Diabetes and the Risk of Peritonitis on PD

    In contrast to earlier reports, a single-center study of PD patients between 1980 and 2012 (by era: 1980-’93, 1994-’04, 2005-12) found that while PD-associated peritonitis was higher among patients with diabetes in the earlier two eras, there were no differences in recent years.

    Read the abstract » | (added 2020-01-09)

    Tags: PD, Peritonitis, Diabetes

  • Impact of a Nurse-led Protocol on PD Fluid Overload

    Among PD patients divided into a group symptomatic of fluid overload (>2L; n=53) and a group that was not (n=50), a 12-week nurse-led education and motivation intervention—with hypertonic cycles for short-term relief of fluid overload—significantly reduced overhydration. Knowledge and adherence were both significantly improved as well.

    Read the abstract » | (added 2020-01-09)

    Tags: Fluid Overload, Hypertonic Cycles, Over Hydration

  • PD vs. In-center HD for Sudden Cardiac Death

    A Korean registry study of 132,083 PD and in-center HD patients followed between 1985 and 2017 analyzed 34,532 deaths. Sudden cardiac death (SCD) was responsible for 19.6% of deaths on PD and 22.2% of deaths on in-center HD. Even after adjusting for age and comorbidities, the risk of SCD was higher with HD.

    Read the abstract » | (added 2020-01-09)

    Tags: PD, In center HD, Sudden Cardiac Death

  • First European Patients Using Nocturnal Home HD with Low-flow Dialysate

    A retrospective analysis looked at 21 patients using low-flow dialysate for nocturnal home HD and followed for a minimum of 12 months. Participants had a mean dialysis duration of 28 hours per week; most used alternate nights and 50-60 L of dialysate per session. Use of phosphate binders and blood pressure medications was significantly reduced, and no patient safety events were reported.

    Read the abstract » | (added 2020-01-09)

    Tags: Low flow Dialysate, Nocturnal Home HD, Phosphate Binders, Blood Pressure Medication

  • Home HD: Hospitalizations and Technique Survival

    In a Swedish registry study, patients initiating PD (n=456), home HD (n=152), and in-center HD (IHD; n=608) were matched by age, sex, comorbidity, and start date. Patients using home HD had significantly lower hospital admissions and days than those doing PD or IHD (1.7, 12 days vs. 2.8, 20 days and 2.2, 14 days respectively). Home HD patients also had significantly fewer admissions for cardiovascular diagnoses or infectious disease, as well as significantly longer technique survival.

    Read the abstract » | (added 2020-01-09)

    Tags: PD, Home HD, In center HD, Hospital Admissions, Cardiovascular Diagnosis, Infectious Disease, Technique Survival

  • A Novel Surgical Technique for Urgent Start PD

    Placing a PD catheter with a double purse-string around the inner cuff was safe and feasible for urgent start PD, finds a study of 135 catheter insertions between 2011 and 2018. Double-cuffed straight Tenckhoff catheters were implanted surgically or semi-surgically using the double purse-string technique, and the incidence of leakages, dislocations, peritonitis, and exit-site infection were low. There were no bleeding events, bowel perforations, or hernia formations.

    Read the abstract » | (added 2020-01-09)

    Tags: PD Catheter, Double Purse string, Urgent Start PD

  • Simultaneous Hernia Repair and PD Catheter Placement

    Taking care of two surgeries at once saves a procedure, recovery time, and costs. Among 123 patients who had catheters placed at a single center over a 4-year period, 23 (19%) had hernias. Across the 23, 27 procedures were done combining hernia repair with PD catheter placement. None of the hernias recurred, and there were no early surgical site infections. Five of the patients developed new hernias at other sites, but after a median of about 3 years, 96% of the catheters were still working.

    Read the abstract » | (added 2019-12-10)

    Tags: Hernia Repair, PD Catheter Placement, Outcome

  • European Patients Live Longer with Extended HD Treatments

    Compared to standard in-center HD, patients from eight European countries who dialyzed for 6+ hours thrice weekly lived longer. Of 142,460 patients, 1,338 did extended HD. Compared to in-center HD (13.5/100 person-years), crude mortality for extended HD (6.0/100 person-years) was significantly better. Overall, those treated with extended treatments were 73% more likely to have survived.

    Read the abstract » | (added 2019-12-10)

    Tags: Survival, Extended hours Hemodialysis, Haemodialysis, ERA EDTA Registry

  • In-center Nocturnal HD: Fewer Complications than PD in Patients with PKD

    An analysis that matched PDK patients who did conventional HD (26) or PD (26) to in-center nocturnal HD (NHD; 13) found no significant difference in mortality—but after a median follow up of 5.5 years, NHD had significantly fewer complications than PD—and higher serum albumin levels as well.

    Read the abstract » | (added 2019-12-10)

    Tags: Polycystic Kidney Disease, Conventional Dialysis, In center Nocturnal HD, Nocturnal Hemodialysis, Mortality

  • PD—Controlling Volume to Reach Normal Hydration Protects the Heart

    Reanalysis of data from a multicenter, prospective, randomized controlled trial looked at fluid control in PD in 151 patients followed for a year. While most (120) reached normal hydration levels as measured by bioimpedance analysis, those who did not had significantly higher left atrial diameter—and a lower left ventricular ejection fraction at the end of the study.

    Read the abstract » | (added 2019-12-10)

    Tags: Fluid Management, Cardiovascular Risk, PD, Peritoneal Dialysis, Bioimpedance Spectroscopy