Weighing PD Catheter Techniques: Surgical vs. Percutaneous

Which is better for placement of a PD catheter—surgery, or use of a tiny incision and guidewire to push the tube through the skin (percutaneous). An analysis of 10 studies with 1,626 patients found no difference in 1-year catheter survival or the rate of peritonitis, tunnel/exit site infection, leaks, obstructions, bleeding, or hernias between the two techniques. But, there were fewer mechanical problems with the percutaneous approach.

Read the abstract » | (added 2016-08-09)

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Overhydration and Mortality Risk on PD

When PD does not remove enough water, the resulting overhydration is a major risk factor for death. A study of 54 PD patients between 2008 and 2015 measured with bioimpedance technology were divided into normohydrated and overhydrated groups. Older age, low diastolic blood pressure and overhydration predicted mortality.

Read the abstract » | (added 2016-08-09)

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Silk Filter for the PD WAK

A urease silk fibroin filter has been tested with a wearable artificial kidney (WAK) for PD. In lab analysis, the filter removed more than 50% of urea from a 50 mg/dL urea solution, and 90% after 24 hours.

Read the abstract » | (added 2016-08-09)

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PD or In-Center HD: Which is Better for Transplant?

An analysis of 12 studies found that doing PD before a transplant had significanlty less delayed graft function than those who did standard in-center HD. While on dialysis, PD had better 5-year survival than standard HD, too. There were no differences in the rates of acute rejection or transplant survival. Watch a Video Journal Club of this study on 'Cappuccino with Claudio Ronco'

Read the abstract » | (added 2016-07-12)

Tags: Hemodialysis

Nocturnal HD Improves Nutritional Status

A metaanalysis was conducted of 9 studies with 229 patients who switched from standard to nocturnal HD. Those on nocturnal HD had significantly higher levels of serum albumin and protein and energy intake.

Read the abstract » | (added 2016-07-12)

Tags: Hemodialysis

Independence, Flexibility and Quality of Life Matter to Patients

For the PCORI-funded Empowering Patients on Choices for Renal Replacement Therapy (EPOCH-RRT), 180 people not yet on dialysis or using standard HD or PD were interviewed to identify the factors in their choice of a dialysis option. Independence, quality and quantity of life, and daily schedule flexibility mattered most—and 47% of those on standard HD said the choice had not been theirs. (NOTE: Ironically, the EPOCH-RRT decision aid omits home HD, an option that offers independence, quality of life, better survival, and schedule flexibility, as we have blogged here and here).

Read the abstract » | (added 2016-07-12)

Tags: Hemodialysis

For HD Survival, Home Beats In-Center

An observational study looked back at 41 incident patients starting home HD and matched them to patients starting in-center HD by sex, age, comorbidity, and start date. Mean survival on home HD was 17.3 years, vs. 13 years in-center. Home HD patients also had significantly lower phosphate levels and did not require blood pressure medications.

Read the abstract » | (added 2016-07-12)

Tags: Hemodialysis

A New Way to Correct PD Catheter Malposition and Blockage

Researchers in China developed a new, minimally invasive technique to reposition and unblock PD catheters. Tested in 16 PD patients, a surgeon made a small (3cm) incision under local anesthesia, disected the tissue, and pulled out the catheter. Adhesions were separated and a new catheter placed with forceps and stitched in place. After 6 months, all of the catheters were working.

Read the abstract » | (added 2016-07-12)

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PD Survival and Serum Sodium – Not What You Might Think

In an analysis of 4,687 people on PD between 2007 and 2011, those whose serum sodium levels were <140 mEq/L had a higher death rate than those with higher levels. Further studies are needed to see if correcting the sodium levels helps people live longer on PD.

Read the abstract » | (added 2016-07-12)

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Outset Medical Tablo Human Factors Testing

Journal articles don’t tend to give product names, so we read between the lines to tell you that human factors testing on Outset’s Tablo home HD machine found 2.9 errors for patients—and 4.4 for nurses or technicians—out of 1,710 opportunities for error. None of the errors was safety related.

Read the abstract » | (added 2016-06-08)

Tags: Hemodialysis