Journal Watch
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APD May Rapidly Improve Left Heart Failure
A single-center observational study of 47 CAPD patients with left-sided heart failure found that using a cycler for short-term APD improved ultrafiltration significantly in just 3 days.
Read the abstract » | (added 2018-06-12)
Tags: CAPD, Cycler, Short term APD, Ultrafiltration
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Whey Protein for PD Malnutrition
A 6-month multicenter, randomized controlled trial tested protein powder plus dietary counseling vs. counseling only for CAPD patients with low serum albumin and BMI. Significantly more of the protein powder group were able to take in enough protein, and they also had significant increases in serum urea and a normalized protein catabolic rate.
Read the abstract » | (added 2018-06-12)
Tags: Malnutrition, Peritoneal Dialysis, Protein Supplementation, Whey Protein
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New Ideas for Incremental PD
Starting incremental PD without the exclusive focus on residual plus peritoneal clearances may ease transitions of new patients onto dialysis—and reduce our “obsession” with small moleule kinetics.
Read the abstract » | (added 2018-06-12)
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Residual Kidney Function and Sleep Apnea Severity in PD
A small (n=15), exploratory study of 15 APD patients with home apnea monitors found obstructive sleep apnea in 33%, which correlated with having less residual renal function.
Read the abstract » | (added 2018-06-12)
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PKD and PD – a Metaanalysis
Among 9 studies totaling 7,197 patients—of whom 882 had polycystic kidney disease—survival was better among the PKD patients. There were no differences in peritonitis or technique survival between those who did and did not have PKD, though those with PKD did have a higher risk of hernias.
Read the abstract » | (added 2018-06-12)
Tags: PKD, PD, Metaanalysis, Polycystic Kidney Disease
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Is the Future Near? Portable Dialysis and Implantable Devices
Portable and wearable PD and HD devices are in development that have the potential to improve patient mobility and autonomy, and perhaps increase technique survival. Bioartificial kidneys that may partly replace some of the endocrine functions of kidneys are on a longer development horizon, followed by miniaturized, implantable devices. Multiple challenges must be overcome for any of these options to become available.
Read the abstract » | (added 2018-05-11)
Tags: Bioartificial Kidney, Implantable Artificial Kidney, Renal Replacement Therapy, Wearable Artificial Kidney
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35-year Patient Survival on Home HD
A case study reports on the 35-year survival of a man with Alport’s syndrome who uses thrice-weekly conventional home HD—and still works 6-8 hours per day at age 65—despite no residual kidney function.
Read the abstract » | (added 2018-05-11)
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Head to Head: 8-hour Hemodialysis vs. 4-hour Hemodiafiltration
A randomized trial assigned 12 nocturnal HD patients to either two weeks of 8-hour HD or 4-hour HDF, followed by a crossover to the other option. Participants were also randomized to one of two dialyzers: a Fresenius FX80 or a Nipro Elisio. The 8-hour HD treatments removed significantly more urea and creatinine. But, the HDF removed more FGF23—and several other toxin levels were the same. The FX80 dialyzer cleared somewhat more B2M.
Read the abstract » | (added 2018-05-11)
Tags: Nocturnal HD, Extended hours Haemodialysis, Haemodiafiltration
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HD at Home—Review of Current Machines
A new review articles compares and contrasts home HD machine options.
Read the abstract » | (added 2018-05-11)
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High Peritoneal Transport and Long-term PD Outcomes
Among 470 patients who did PD for up to 10 years in Hong Kong, the peritoneal transport rate was able to differentiate survivors. After the first few years of PD, having high peritoneal transport became a significant risk factor for mortality.
Read the abstract » | (added 2018-05-11)