Journal Watch
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U.S Nephrologists on When to Start Dialysis
While clinical practice guidelines recommend starting dialysis mainly on signs and symptoms, almost half of 255 nephrologists surveyed relied solely on eGFR. For them, a level of 8.4 meant dialysis—even in the absence of symptoms.
Read the abstract » | (added 2022-12-19)
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Serum albumin at 1 Year Predicts Long-term CAPD Outcomes
Among 436 patients using CAPD and followed for at least a year (48.25 + 24.05 months), each 1 g/dL increase in serum albumin at 1 year after PD start reduced the risk of death by 8.7%.
Read the abstract » | (added 2022-12-19)
Tags: Peritoneal Dialysis , Serum Albumin, CAPD, Mortality
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Home HD Begins in Mainland China
Intrigued by observational studies suggesting better survival for home HD than in-center HD or PD—and reduced COVID exposure—a clinic in China established a training center and enrolled six patients. Patients were monitored by home visits, online, and by outpatient services. After an average of 16 months of training, three patients began independent dialysis at home, with no serious adverse events. Blood levels remained stable.
Read the abstract » | (added 2022-12-19)
Tags: Home HD, In center HD, PD, Infection, Mainland China
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Cycler vs. Manual PD for Survival
A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.
Read the abstract » | (added 2022-12-19)
Tags: Peritoneal Dialysis, PD, Modality, Automated Peritoneal Dialysis, APD, Continuous Ambulatory Peritoneal Dialysis, CAPD, All cause Mortality, ACM, PD Failure, Survival
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Incremental PD (IPD) and Preservation of Residual Kidney Function
A single-center, retrospective study of IPD vs. standard PD (SPD) examined data from 87 patients, about 2/3 on IPD, with a median follow up of 23 months. IPD was associated with longer technique survival and significantly higher GFRs at 6 months and after 24 months.
Read the abstract » | (added 2022-12-19)
Tags: Incremental PD, IPD, Residual Kidney Function, Technique Survival
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A New PET Resource
How and why are peritoneal equilibrium tests (PETs) done? What are the various iterations? What can be learned from the results? Find out in this new review.
Read the abstract » | (added 2022-11-16)
Tags: Peritoneal Equilibrium Tests, PETs
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Urine Output on PD Predicts Solute Removal
In an observational study of 93 people on CAPD (n=34) or APD (n=59) who still made urine, 24-hour urine collection correlated positively with removal of wastes + residual clearance. There was no significant difference between CAPD and APD.
Read the abstract » | (added 2022-11-16)
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Which Modality is Better Between Transplants: PD or HD?
Among 776 people in a registry who received a second kidney transplant, 656 did standard in-center hemodialysis (HD) between transplants, 72 did PD, and 48 went immediately to a second transplant. Those who did PD or went directly to a second transplant had better adjusted survival than those on HD.
Read the abstract » | (added 2022-11-16)
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Extended HD and Nutrition
An attempt to do a metaanalysis of the literature on the impact of daily and nocturnal HD (15+ hours per week) on nutritional status failed due to lack of sufficient high quality papers. In five studies of nocturnal and/or daily HD—three in-center and two at home—lean body mass improved significantly and one study found deficiency in water-soluble vitamins.
Read the abstract » | (added 2022-11-16)
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The Predictive Value of Early, Non-infectious PD Complications
A prospective, multicenter cohort study of 1,596 people starting PD in New Zealand from 2014 to 2018 (inclusive) looked at survival and time on PD of those who had catheter-related exit site dialysate leaks or other leaks within 30 days of PD start. Peritonitis-free survival, first PD catheter survival, and tunnel infection free survival were secondary outcomes. Among the 102 with an early complication, overall mortality, the rate of stopping PD, and first catheter failure were all higher.
Read the abstract » | (added 2022-11-16)
Tags: PD, Survival, Peritonitis free Survival, First PD Catheter Survival, Tunnel Infection Free Survival, Early Catheter related Complication