Journal Watch - PD
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Zinc Deficiency and Anemia in PD
Analysis of data from 164 adults on PD set a target hemoglobin level of 11-13g/dL and ESA dosage as low- (<120 µg/month) or high-dose (>120 µg/month). Zinc deficiency was defined as a serum zinc level <60 µg/dL. In the low-dose ESA, non-zinc deficient group, 48.2% of patients achieved the target hemoglobin level, while in in the high-dose ESA, zinc-deficient group, just 12.2% did. These results were not changed with the addition of serum albumin C-reactive protein, or TSAT. The authors conclude that “serum zinc levels should be routinely monitored in patients with ESA-hyporesponsive anemia.”
Read the abstract » | (added 2026-02-17)
Tags: Zinc Deficiency, Anemia, PD
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Prevalence of Anxiety in PD
Anxiety is less often measured than depression, but can be even more difficult for patients. A small study (n=85 PD patients), suggests that some degree of anxiety may be more prevalent than is currently realized. While about half (50.6%) reported minimal anxiety on the Beck Anxiety Inventory, the remaining half were split between mild (25.9%), moderate (14.1%) and severe (9.4%) anxiety. The authors suggest early diagnosis and management of mood disorders in ESRD patients.
Read the abstract » | (added 2026-01-16)
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Body Mass Index and PD: A Meta-analysis
Analysis of adjusted data from 18 studies found that underweight PD patients had a significantly higher risk of mortality than those with normal BMI, though obesity did not. However, obese PD patients had a significant increase in the risk of peritonitis. Neither underweight nor obesity increased the risk of technique failure or transfer to HD.
Read the abstract » | (added 2025-11-11)
Tags: Body Mass Index, PD, Meta analysis
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Diabetes + PD + Self-management: Theory of Planned Behavior (TPB)
Semi-structured interviews formulated with TPB were conducted with 16 diabetic kidney disease (DKD) PD patients. Analysis identified 3 themes and 7 sub-themes related to physical and mental perception, emotions, subjective norm, continuity of care, social feedback, perceived behavioral control, and limitations on external resources. Strengthening positive feedback and social support can improve active patient participation in decision-making.
Read the abstract » | (added 2025-08-21)
Tags: Diabetic Kidney Disease, Diabetes, PD, Self management, Theory Of Planned Behavior
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Black and Latino Patients: Staying on PD
Black and Latino patients are disproportionately affected by ESKD, less likely to use PD, and more likely to switch to in-center HD if they do start PD. In-depth, semistructured interviews with twelve Black and eight Latino patients who were currently or previously receiving PD found that poor mental health, medicalization of the home, and language and cultural barriers were factors in PD dropout.
Read the abstract » | (added 2025-08-21)
Tags: Ethnicity, ESKD, PD, PD Dropout
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PD or HD: Which Has the Higher Risk of Infective Endocarditis (IE)?
In a retrospective analysis of 215,965 people with ESRD and more than a million age- and sex-matched people without it, IE incidence was lower in the PD group. For those doing HD, the IE incidence was lowest for those dialyzing with an AVF.
Read the abstract » | (added 2025-07-16)
Tags: ESRD, Infective Endocarditis, HD, PD
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BMI, Diabetes, and Mortality: HD and PD Differ
Among 3,235 patients with diabetes on dialysis followed for 3.9 + 3.5 years, most (2,452) were on HD, with 783 on PD. During the study, 53% (1,688) patients died (1,275: HD; 413: PD). In HD patients, mortality risk was higher in those with BMIs <18.5 kg/m2 and lower when BMI ranged from 25.1 to 40 kg/m2. No relationship was found between BMI and mortality risk on PD.
Read the abstract » | (added 2025-06-11)
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Seniors, PD, and Inappropriate Prescriptions
No study has previously assessed what percent of people over age 65 on PD are receiving the correct doses of prescribed drugs. Unfortunately, this study finds that a large minority may not be.
Read the abstract » | (added 2025-04-23)
Tags: Seniors, PD, Inappropriate Prescriptions, Correct Dose
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Uptake of Home Dialysis After Kidney Transplant Failure by Sex
An ANZDATA registry study analyzed dialysis after transplant failure of 3,521 patients from 2000 to 2020. While 38% of the patients were female, 12 months after transplant failure, 14% were using PD and 12% were using home HD. Males were 55% less likely to choose PD after transplant failure and 66% more likely to choose home HD. These disparities were greater in low SES regions.
Read the abstract » | (added 2025-03-13)
Tags: Gender, PD, Home HD, Transplant Failure
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Pet Cats and Peritonitis—a Non-starter for PD?
The answer might surprise you. In a retrospective registry study in France, 52 PD patients who developed cat-related peritonitis were matched with 208 controls whose PD peritonitis was due to other causes. After analysis, pet-related peritonitis had lower risks of death or transfer to HD and a higher rate of transplant than other-cause peritonitis. The authors concluded that, while cats may cause peritonitis, having pets at home should not be considered a reason to refuse patients PD.
Read the abstract » | (added 2024-11-21)
Tags: Pets, Cats, Peritonitis, Pet related Peritonitis, PD, Technique Survival