Journal Watch

  • Local Anesthetic for PD Catheter Placement

    A study of 27 people tested the feasibility of using mepivacaine 1% (which lasts longer than lidocaine) plus sedation with Remifentanil for PD catheter placement. None of the 27 needed to convert to general anesthesia, and all of the catheters worked with no leakage.

    Read the abstract » | (added 2021-11-12)

    Tags: PD Catheter, Mepivacaine, Remifentanil

  • New Clinical Practice Guidelines for Exercise on PD

    The International Society for Peritoneal Dialysis and the Global Renal Exercise Network have teamed up to grade and review the literature and clinical experience to help people on PD stay physically active safely. With sparse quality evidence available, the new guidelines are largely opinion based, and cover timing of exercise relative to PD (i.e., empty or full); impact of exercise on mental health, weight, frailty, etc.; exercise nutrition, and potential adverse PD outcomes.

    Read the abstract » | (added 2021-11-12)

    Tags: Peritoneal Dialysis, Exercise, Physical Activity, PD Outcomes

  • Minority of UK Dialyzors Would Choose Standard HD Schedule

    Given the choice of 12 different scheduling options, just 38% of 183 people doing standard in-center HD would always choose to keep doing what they were doing. Of the remainder, after being informed of the survival and quality of life benefits of more dialysis, 27.1% would choose longer treatments thrice weekly, and 34.4% would choose four 4-hour treatments per week.

    Read the abstract » | (added 2021-11-12)

    Tags: In center HD, More Frequent Hemodialysis, Longer Treatments

  • Some Antihypertensive Meds Reduce GI Bleeds in PD

    GI bleeding is more likely in people with CKD. A study of 734 people on PD were followed to see if use of an ACE-inhitor or angiotensin receptor blocker (ARB) would reduce the incidence. After an 8-year follow-up, those who were taking these meds had a significantly lower rate of GI bleeding.

    Read the abstract » | (added 2021-11-12)

    Tags: GI Bleeding, CKD, PD, ACE inhitor, Angiotensin Receptor Blocker

  • Italians Improve on Daily Home HD

    As in the U.S., the Italian Ministry of Health has home dialysis as a primary objective. In a 2-year study of seven people switched to six times per week daily home HD, significant improvements began to appear almost immediately. After 3-6 months, bone mineral balance and blood pressure were better, PTH levels and use of phosphate binders dropped, and the participants needed less rhEPO.

    Read the abstract » | (added 2021-11-12)

    Tags: Home Dialysis, Daily Home HD, RhEPO, Mineral Balance, Blood Pressure, PTH Levels

  • Health-related Quality of Life Better on PD than Standard HD in Morocco City

    Compared to 71 people using standard HD, 20 doing PD had significantly better physical and mental component scores and staff encouragement, and significantly lower burden of kidney disease scores.

    Read the abstract » | (added 2021-11-12)

    Tags: Standard HD, PD, Component Scores, Burden Of Kidney Disease Scores

  • Lower salt diet and residual kidney function on PD

    Sixty-two people on PD were divided into three groups by salt intake (<6 grams/day, 6-8 grams/day, and>8 grams/day). One year later, those with the highest salt intake had the fastest decline in residual kidney function.

    Read the abstract » | (added 2021-10-13)

    Tags: PD, Salt Intake, Residual Kidney Function

  • Low serum vitamin D levels, anemia, and inflammation on PD

    When 62 people on PD were compared to 56 healthy volunteers, the PD group had significantly lower vitamin D levels—and significantly higher inflammatory markers (HS-CRP, IL-6, and TNF-α). The researchers concluded that low vitamin D levels contribute to anemia, oxidative stress, and microinflammation.

    Read the abstract » | (added 2021-10-13)

    Tags: PD, Vitamin D, Inflammatory Markers, Anemia, Oxidative Stress, Microinflammation

  • Home HD Core Curriculum, 2021

    COVID-19 and policy changes have revived interest in home HD, so nephrologists need to better understand the therapy. This article focuses on factors in successful training and retention, including benefits, pitfalls, challenges, new equipment, prescriptions, and more.

    Read the abstract » | (added 2021-10-13)

    Tags: HHD, Home HD, Training

  • PD and home HD patients less stressed by COVID-19

    Does the social isolation of PD or home HD contribute to a negative psychosical impact from COVID? Apparently not. Forty patients (85% on home HD) responded to a COVID impact survey sent to 98 home HD and 43 PD patients in Toronto. About 80% rated their dialysis satisfaction at 8/10 or higher, had infrequent anxiety or depression, felt dialysis had minimal impact on their lives, and were almost always happy with their family interactions. Just 9% were often worried about caregiver burden. The authors suggest that home is “the optimal form of dialysis.”

    Read the abstract » | (added 2021-10-13)

    Tags: Home HD, COVID 19, Coronavirus