Journal Watch - All cause Mortality
Serum Phosphorus and Survival on PD
Data from 5,847 PD patients between 2014-2017 from seven countries in the PDOPPS study found that compared to an optimal range of 3.5-4.5mg/dL, the hazard ratio (HR) for all-cause mortality was 19% higher when phosphorus was 5.5-6.5 and 53% higher when phosphorus was greater than 6.5. When 6 months of data were examined, the linkage was even stronger.
Read the abstract » | (added 2023-02-13)
Cycler vs. Manual PD for Survival
A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.
Read the abstract » | (added 2022-12-19)
HD Dose and Patient Survival: More is Better
Even using spKt/V—a flawed measure that considers only urea—a study of 558 standard HD patients from 2015 to 2020, of whom 214 died, found that a higher dose of dialysis reduced the risk of all-cause mortality by 33%.
Read the abstract » | (added 2022-09-13)
Too-high OR Too-low LDL Cholesterol and Survival on PD
A retrospective study in China looked at data from 3,565 people starting PD from 2005 to 2020. Both higher and lower levels of LDL-C were linked with higher all-cause and cardiovascular mortality. Malnutrition and low LDL-C was especially risky.
Read the abstract » | (added 2022-08-11)
Urgent Start PD Takes on Urgent Start HD—Which One Wins?
A new meta-analysis examines survival vs. urgent start HD (which is experienced by an estimated 50%-60% of U.S. dialyzors). Pooled data from seven studies identified “a statistically significant reduced risk of all-cause mortality in patients undergoing urgent-start PD as compared to urgent-start HD.” While infectious complications did not differ, there was a significantly reduced risk of mechanical complications with PD.
Read the abstract » | (added 2022-05-12)