Journal Watch - CAPD
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CAPD vs. APD: Meta-analysis Sheds No New Light
A Cochrane Kidney and Transplant Register of Studies update identified two new randomized controlled trials (n=131) to include, one with 6-month follow-up and one with 24-month follow-up. Both studies had mostly low risk of bias. Conclusions about differences in CAPD and APD outcomes for death, hospitalizations, peritonitis, modality change, residual kidney function, health-related quality of life, overhydration, blood pressure, and a host of other outcomes were all based on low to very low certainty evidence.
Read the abstract » | (added 2024-10-15)
Tags: CAPD, APD, Modality Outcomes
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Risk Factors for Cognitive Impairment in Peritoneal Dialysis
A retrospective analysis of 268 CAPD patients from January 2020 to September 2023. categorized participants into a cognitively impaired (CI; 58.2%) and a cognitively normal (CN) group. Logistic regression analysis identified male gender, older age, lower educational attainment, hypercholesterolemia, and elevated high-sensitivity C-reactive protein levels as independent risk factors for CI in CAPD patients (P < .05), while dialysis duration and residual renal function were protective against CI (P < .05).
Read the abstract » | (added 2024-08-16)
Tags: CAPD, Cognitive Impairment, Logistic Regression Analysis, Risk Factors
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Carbon Footprint of CAPD vs. CCPD/APD in Australia
In the U.S., CAPD has been losing ground to cycler PD for a decade or more. But, an Australian analysis finds that CAPD has about a one-third lower carbon footprint than use of a PD cycler. With Baxter equipment, the manufacture and disposal of PD fluids and consumables were estimated at 1,992 Kg CO2 equivalent emissions for cycler PD; and just 1,245 Kg CO2 equivalent emissions for manual PD.
Read the abstract » | (added 2024-05-09)
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Frequency of Sexual Dysfunction on PD
A study enrolled 201 people who did CAPD for 3+ months (49 females and 65 males), with slightly more than half (n=114) under age 65). Gender-appropriate surveys administered in person, along with the SF-36 and Beck Depression Inventory (BDI) revealed that almost 90% of women and almost 88% of men reported sexual dysfunction. Depression was highly prevalent as well. The authors concluded that not discussing and treating sexual dysfunction could adversely affect quality of life.
Read the abstract » | (added 2023-01-10)
Tags: CAPD, Depression, Sexual Dysfunction, Quality Of Life
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Cycler vs. Manual PD for Survival
A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.
Read the abstract » | (added 2022-12-19)
Tags: Peritoneal Dialysis, PD, Modality, Automated Peritoneal Dialysis, APD, Continuous Ambulatory Peritoneal Dialysis, CAPD, All cause Mortality, ACM, PD Failure, Survival
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Urine Output on PD Predicts Solute Removal
In an observational study of 93 people on CAPD (n=34) or APD (n=59) who still made urine, 24-hour urine collection correlated positively with removal of wastes + residual clearance. There was no significant difference between CAPD and APD.
Read the abstract » | (added 2022-11-16)
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Which Form of PD Has a Higher Risk of Peritonitis?
If you guessed CAPD because there are more exchanges to perform, you are correct, finds a study that matched 106 APD to 106 CAPD patients and followed them for 3 years. During the study period, there were 64 cases of peritonitis, and the risk was 30% higher among those who did CAPD.
Read the abstract » | (added 2020-11-12)
Tags: PD, Peritoneal Dialysis, CAPD
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Antibiotics Before Colonoscopy May Reduce Peritonitis Risk in PD Patients
In a retrospective study of 236 CAPD patients who had colonoscopies, 9 developed peritonitis within a week of the procedure. No patient who received prophylactic antibiotics developed peritonitis. Randomized controlled trials are recommended.
Read the abstract » | (added 2019-11-16)
Tags: CAPD, Colonoscopy, Peritonitis, Prophylactic Antibiotics, Polypectomy, Endoscopic Mucosal Resection
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RCT: Which Works Best, Straight or Coiled PD Catheters?
A metaanalysis recently found that straight catheters were better, and an RCT of 308 CAPD patients randomly assigned to receive a straight (n=153) or coiled (n=155) catheter corroborates that finding. After a mean follow-up of 21 months, straight PD catheters caused almost 9 times less dysfunction or drainage failure (0.7% vs. 5.8%) with less pain than coiled catheters. Both catheters had a similar risk of peritonitis.
Read the abstract » | (added 2019-09-11)
Tags: Catheter, Randomized Controlled Trial (RCT), PD, CAPD
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Does RRF affect quality of life in CAPD?
The SF-36 was given to 120 adult patients on CAPD for at least 3 months, divided into a group with and without residual renal function. There were no correlations between RRF and total SF-36 scores. However, SF-36 scores did correlate with measures of inflammation, fluid overload, and malnutrition. Read the abstract.
Read the abstract » | (added 2018-07-13)

