Journal Watch - CAPD
CAPD vs. APD: Meta-analysis Sheds No New Light
A Cochrane Kidney and Transplant Register of Studies update identified two new randomized controlled trials (n=131) to include, one with 6-month follow-up and one with 24-month follow-up. Both studies had mostly low risk of bias. Conclusions about differences in CAPD and APD outcomes for death, hospitalizations, peritonitis, modality change, residual kidney function, health-related quality of life, overhydration, blood pressure, and a host of other outcomes were all based on low to very low certainty evidence.
Read the abstract » | (added 2024-10-15)
Tags: CAPD, APD, Modality Outcomes
Risk Factors for Cognitive Impairment in Peritoneal Dialysis
A retrospective analysis of 268 CAPD patients from January 2020 to September 2023. categorized participants into a cognitively impaired (CI; 58.2%) and a cognitively normal (CN) group. Logistic regression analysis identified male gender, older age, lower educational attainment, hypercholesterolemia, and elevated high-sensitivity C-reactive protein levels as independent risk factors for CI in CAPD patients (P < .05), while dialysis duration and residual renal function were protective against CI (P < .05).
Read the abstract » | (added 2024-08-16)
Tags: CAPD, Cognitive Impairment, Logistic Regression Analysis, Risk Factors
Carbon Footprint of CAPD vs. CCPD/APD in Australia
In the U.S., CAPD has been losing ground to cycler PD for a decade or more. But, an Australian analysis finds that CAPD has about a one-third lower carbon footprint than use of a PD cycler. With Baxter equipment, the manufacture and disposal of PD fluids and consumables were estimated at 1,992 Kg CO2 equivalent emissions for cycler PD; and just 1,245 Kg CO2 equivalent emissions for manual PD.
Read the abstract » | (added 2024-05-09)
Frequency of Sexual Dysfunction on PD
A study enrolled 201 people who did CAPD for 3+ months (49 females and 65 males), with slightly more than half (n=114) under age 65). Gender-appropriate surveys administered in person, along with the SF-36 and Beck Depression Inventory (BDI) revealed that almost 90% of women and almost 88% of men reported sexual dysfunction. Depression was highly prevalent as well. The authors concluded that not discussing and treating sexual dysfunction could adversely affect quality of life.
Read the abstract » | (added 2023-01-10)
Tags: CAPD, Depression, Sexual Dysfunction, Quality Of Life
Cycler vs. Manual PD for Survival
A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.
Read the abstract » | (added 2022-12-19)
Tags: Peritoneal Dialysis, PD, Modality, Automated Peritoneal Dialysis, APD, Continuous Ambulatory Peritoneal Dialysis, CAPD, All cause Mortality, ACM, PD Failure, Survival
Urine Output on PD Predicts Solute Removal
In an observational study of 93 people on CAPD (n=34) or APD (n=59) who still made urine, 24-hour urine collection correlated positively with removal of wastes + residual clearance. There was no significant difference between CAPD and APD.
Read the abstract » | (added 2022-11-16)
Which Form of PD Has a Higher Risk of Peritonitis?
If you guessed CAPD because there are more exchanges to perform, you are correct, finds a study that matched 106 APD to 106 CAPD patients and followed them for 3 years. During the study period, there were 64 cases of peritonitis, and the risk was 30% higher among those who did CAPD.
Read the abstract » | (added 2020-11-12)
Tags: PD, Peritoneal Dialysis, CAPD
Antibiotics Before Colonoscopy May Reduce Peritonitis Risk in PD Patients
In a retrospective study of 236 CAPD patients who had colonoscopies, 9 developed peritonitis within a week of the procedure. No patient who received prophylactic antibiotics developed peritonitis. Randomized controlled trials are recommended.
Read the abstract » | (added 2019-11-16)
Tags: CAPD, Colonoscopy, Peritonitis, Prophylactic Antibiotics, Polypectomy, Endoscopic Mucosal Resection
RCT: Which Works Best, Straight or Coiled PD Catheters?
A metaanalysis recently found that straight catheters were better, and an RCT of 308 CAPD patients randomly assigned to receive a straight (n=153) or coiled (n=155) catheter corroborates that finding. After a mean follow-up of 21 months, straight PD catheters caused almost 9 times less dysfunction or drainage failure (0.7% vs. 5.8%) with less pain than coiled catheters. Both catheters had a similar risk of peritonitis.
Read the abstract » | (added 2019-09-11)
Tags: Catheter, Randomized Controlled Trial (RCT), PD, CAPD
Does RRF affect quality of life in CAPD?
The SF-36 was given to 120 adult patients on CAPD for at least 3 months, divided into a group with and without residual renal function. There were no correlations between RRF and total SF-36 scores. However, SF-36 scores did correlate with measures of inflammation, fluid overload, and malnutrition. Read the abstract.
Read the abstract » | (added 2018-07-13)