ISPD Proposes to Remove PD Toxin Clearance Targets

New ISPD Guidelines suggest that the focus of PD should be patient well-being—not lab values. This change would allow more people to do PD, and focusing on relieving uremic symptoms could help determine which solutes really do matter to quality of life.

Read the abstract » | (added 2023-08-16)

Tags: PD, Patient Well being, Lab Values, Uremic Symptoms, Quality Of Life

Hope Matters in PD

Among 134 patients receiving PD in Hong Kong, those who were working, had a higher income, and were using a cycler for PD had higher hope scores, and there were correlations with age and social support. Higher hope scores were linked with better mental well-being and less severe depression.

Read the abstract » | (added 2023-06-14)

Tags: PD, PD Cycler, Work, Hope Score, Social Support, Mental Well being, Depression

UK Target: 20+% on Home Dialysis

Despite the many benefits of home therapies, PD and home HD remain underused. The UK now recommends a minimum 20% prevalence rate for home dialysis.

Read the abstract » | (added 2023-06-14)

Tags: PD, Home HD, Peritonitis

Serum Phosphorus and Survival on PD

Data from 5,847 PD patients between 2014-2017 from seven countries in the PDOPPS study found that compared to an optimal range of 3.5-4.5mg/dL, the hazard ratio (HR) for all-cause mortality was 19% higher when phosphorus was 5.5-6.5 and 53% higher when phosphorus was greater than 6.5. When 6 months of data were examined, the linkage was even stronger.

Read the abstract » | (added 2023-02-13)

Tags: PD, Serum Phosphorus, PDOPPS, Hazard Ratio, All cause Mortality

Cycler vs. Manual PD for Survival

A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.

Read the abstract » | (added 2022-12-19)

Tags: Peritoneal Dialysis, PD, Modality, Automated Peritoneal Dialysis, APD, Continuous Ambulatory Peritoneal Dialysis, CAPD, All cause Mortality, ACM, PD Failure, Survival

The Predictive Value of Early, Non-infectious PD Complications

A prospective, multicenter cohort study of 1,596 people starting PD in New Zealand from 2014 to 2018 (inclusive) looked at survival and time on PD of those who had catheter-related exit site dialysate leaks or other leaks within 30 days of PD start. Peritonitis-free survival, first PD catheter survival, and tunnel infection free survival were secondary outcomes. Among the 102 with an early complication, overall mortality, the rate of stopping PD, and first catheter failure were all higher.

Read the abstract » | (added 2022-11-16)

Tags: PD, Survival, Peritonitis free Survival, First PD Catheter Survival, Tunnel Infection Free Survival, Early Catheter related Complication

Safety of Exercise for Those Who Do PD

A review of 25 studies of exercise in PD found only minor adverse events, mainly short-term muscle or joint pain or fatigue. There were no serious adverse events or signs of harm.

Read the abstract » | (added 2022-09-13)

Tags: PD, Peritoneal Dialysis, Exercise, Benefits, Adverse Events

Too-high OR Too-low LDL Cholesterol and Survival on PD

A retrospective study in China looked at data from 3,565 people starting PD from 2005 to 2020. Both higher and lower levels of LDL-C were linked with higher all-cause and cardiovascular mortality. Malnutrition and low LDL-C was especially risky.

Read the abstract » | (added 2022-08-11)

Tags: PD, LDL C, Cardiovascular Mortality, All cause Mortality, Malnutrition

Risk of Left Ventricular Hypertrophy Tied to Fluid Overload on PD

A single hospital had 226 enrolled PD patients between late 2018 and January 2021. Using bioimpedance analysis and cardiac color Doppler ultrasound, patients were divided into an LVF and a non-LVF group, and into a normal volume and overhydration group. Of participants, 125 (55.3%) had LVH. Overhydration and low hemoglobin levels were independent risk factors for LVH.

Read the abstract » | (added 2022-06-10)

Tags: PD, LVH, Overhydration, Volume Loads

PD Reduced Hospitalization 24% vs. In-center HD with a Catheter

In an 18-month retrospective study, 717 PD patients were matched 1:1 with in-center HD patients using central venous catheters. The matching also included cause of ESKD, race, diabetes status, and insurance. The hospitalization rate was 24% lower for those on PD, and mortality was 15% lower.

Read the abstract » | (added 2022-04-18)

Tags: PD, In center HD, Catheters, Cause Of ESKD, Race, Diabetes Status, Insurance, Hospitalization Rate, Mortality