Journal Watch
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Body Mass Index and PD: A Meta-analysis
Analysis of adjusted data from 18 studies found that underweight PD patients had a significantly higher risk of mortality than those with normal BMI, though obesity did not. However, obese PD patients had a significant increase in the risk of peritonitis. Neither underweight nor obesity increased the risk of technique failure or transfer to HD.
Read the abstract » | (added 2025-11-11)
Tags: Body Mass Index, PD, Meta analysis
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PDOPPS on Incremental PD Starts and Clinical Outcomes
What dose should be offered at the start of incremental PD? An international prospective cohort study assessed 1,365 patients from 128 clinics in seven countries who began standard (63%) or incremental (37%) PD within3 months of January 1, 2014 until December 31, 2017. There was no significant difference in transfer to HD between the standard PD (15%/year) and incremental PD (14%/year), nor were there differences between groups in peritonitis or mortality.
Read the abstract » | (added 2025-11-11)
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Impact of Embedded PD Catheters on Peritonitis and Mortality
Moncrief and Popovich pioneered a buried PD catheter technique (inexplicably abbreviated as SMAP). In a study, outcomes of 285 consecutive patients who had PD catheters implanted either directly (n=96) or via SMAP (n=189) were analyzed retrospectively. Both the risks of peritonitis and mortality were significantly lower in the SMAP group.
Read the abstract » | (added 2025-07-16)
Tags: Embedded PD Catheters, Peritonitis, Mortality, Moncrief And Popovich Technique
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U.S. PD Outcome Trends: 2009 to 2018
A USRDS analysis of data from 101,640 incident PD patients found a decrease in overall mortality from 11% (2009) to 8.4% (2018). The probability of switching to in-center HD a year after PD initiation also dropped by about 2% in patients under 75 years old.
Read the abstract » | (added 2025-07-16)
Tags: Chronic Dialysis, Incident PD , Mortality, Peritoneal Dialysis, Clinical Epidemiology
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Urgent-start HD (USHD) vs. Urgent-start PD (USPD): A Meta-analysis
Compiled data from seven studies and 1,338 patients found significantly fewer complications (infectious and noninfectious) and mortality with USPD than with USHD. The authors concluded that USPD patients “could potentially function as an appropriate replacement for USHD.”
Read the abstract » | (added 2025-07-16)
Tags: Urgent start HD, Urgent start PD
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PD Outcomes Predicted by the Triglyceride-Glucose (TyG) Index
An index based on low-cost blood tests may help predict mortality, peritonitis, and technical failure on PD. Among 354 CAPD patients stratified into TyG tertiles, the highest tertile experienced significantly higher all-cause and cardiovascular death over a median of 72 months of follow-up than the lowest tertile.
Read the abstract » | (added 2025-07-16)
Tags: PD Outcomes, Triglyceride Glucose Index, Mortality, Peritonitis, CAPD
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BMI, Diabetes, and Mortality: HD and PD Differ
Among 3,235 patients with diabetes on dialysis followed for 3.9 + 3.5 years, most (2,452) were on HD, with 783 on PD. During the study, 53% (1,688) patients died (1,275: HD; 413: PD). In HD patients, mortality risk was higher in those with BMIs <18.5 kg/m2 and lower when BMI ranged from 25.1 to 40 kg/m2. No relationship was found between BMI and mortality risk on PD.
Read the abstract » | (added 2025-06-11)
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Expanded HD (HDx) vs. Online Hemodiafiltration (HDF)
A systematic review and meta-analysis of eight studies (n=614) compared HDx and HDF. While there was no statistical difference in all-cause mortality, creatinine, phosphate, or urea clearance, HDF did significantly reduce β2-microglobulin.
Read the abstract » | (added 2025-05-20)
Tags: HDx, HDF, Middle molecule Clearance
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Laparoscopic vs. Open PD Catheter Placement
Analysis of 11,731 PD catheter insertions from 2013 to 2018 examined the association between type of placement, complications, length of hospital stay, and mortality. During the 5-year period there was a significant increase in laparoscopic PD insertions. Complications were similar between groups, with slightly longer hospital stays for open placements.
Read the abstract » | (added 2025-03-13)
Tags: PD Catheter, Complications, Laparoscopic PD Insertions
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Impact of PD Exchange Volume/Day on Outcomes
A DOPPS cohort study in Japan divided patients into two groups by daily PD dialysate volume (<4L/day; n=98 or >4L/day; n=244). Despite demographic differences between the groups, there were no significant differences in transfers to HD, mortality, hospitalization, peritonitis, or patient-reported outcomes based on volume—thus less volume may be more cost effective.
Read the abstract » | (added 2024-12-11)
Tags: Dialysate Volume, Peritoneal Dialysis Outcomes, Mortality, Patient reported Outcomes