Journal Watch - PD
Must PD Stop when Residual Kidney Function is Gone?
Not necessarily. In a small, physiological study (n=15) of anuric CAPD patients with low Kt/V, fluid status, dietary intake, and nitrogen removal were all assessed. All were able to maintain good nutritional status, with no symptoms of nitrogen retention and good volume control.
Read the abstract » | (added 2022-02-14)
Tags: PD, Residual Kidney Function, CAPD, Kt/V, Fluid Status, Dietary Intake, Nitrogen Removal, Volume Control
PD Helps Kidney Function Recovery
PD is known to help preserve residual kidney function. A study of 981 people on PD and 12,619 on HD in Taiwan looked at which option was more likely to help incident dialyzors recover function. Nearly 5% did recover their kidney function within 3 years—with a better chance for those who did PD.
Read the abstract » | (added 2022-02-14)
Tags: PD, HD, Kidney Function Recovery
Oral Hygiene and Nutritional Status on PD
Clean teeth mattered for nutritional status and hand grip strength in a small study (n=41) of people on PD. Inflamed gums can cause tooth loss and limit what people can eat. Those with dirty to very dirty teeth had poorer nutrition than those with clean or slightly dirty teeth, and their hand grips were weaker. Those with dirty teeth also had more GI symptoms and a higher risk of malnutrition.
Read the abstract » | (added 2021-12-16)
Tags: PD, Tooth Loss, Malnutrition, Gingivitis, Periodontitis
Simplified Half Percutaneous PD Catheter Placement Technique
Use of a simple modified metal trocar was safe and effective in a series of 280 consecutive PD patients followed for 3 years. Taking an average of less than 30 minutes, the new technique was technically successful 99.3% of the time initially, with mechanical complications occurring in 10% during the follow-up period; most commonly catheter malfunction, and 32 episodes of peritonitis (10.4%). By the end of the study, 83.9% lived and still had their initial catheters.
Read the abstract » | (added 2021-12-16)
Tags: PD, Peritoneal Dialysis, Catheter, Half percutaneous Technique
Standard vs. Incremental PD Start: 12-year Retrospective Study
When people start PD with some residual function, is it beneficial not to begin with a full PD prescription? A study looked back at 12 years of people who started PD, 232 standard and 71 intermittent (iPD; 2-3 manual exchanges per day). Those who did iPD had higher residual kidney function than those on standard PD. For people with diabetes, iPD was linked with a survival advantage as well.
Read the abstract » | (added 2021-12-16)
Tags: PD, Residual Function, Intermittent PD, IPD, Diabetes
Low serum vitamin D levels, anemia, and inflammation on PD
When 62 people on PD were compared to 56 healthy volunteers, the PD group had significantly lower vitamin D levels—and significantly higher inflammatory markers (HS-CRP, IL-6, and TNF-α). The researchers concluded that low vitamin D levels contribute to anemia, oxidative stress, and microinflammation.
Read the abstract » | (added 2021-10-13)
Tags: PD, Vitamin D, Inflammatory Markers, Anemia, Oxidative Stress, Microinflammation
Lower salt diet and residual kidney function on PD
Sixty-two people on PD were divided into three groups by salt intake (<6 grams/day, 6-8 grams/day, and>8 grams/day). One year later, those with the highest salt intake had the fastest decline in residual kidney function.
Read the abstract » | (added 2021-10-13)
Tags: PD, Salt Intake, Residual Kidney Function
Residual Kidney Function and Incremental PD
A retrospective cohort study was done of 96 incident PD patients (54 on incremental PD; 42 on standard PD). The incremental PD patients had lower exchange volumes, less glucose load—and longer peritonitis-free survival.
Read the abstract » | (added 2021-09-14)
Tags: PD, Incremental Dialysis, Peritonitis, Residual Kidney Function, Technique Survival
PD After Transplant Failure
We know that PD helps preserve residual kidney function longer: will this work after a failed transplant, too? An 8-year chart review study found no difference between technique survival, peritonitis-free survival, and residual urine in patients with transplant failure who returned to PD (n=18) vs. those who started PD for other reasons (n=163).
Read the abstract » | (added 2021-09-14)
Tags: PD, Residual Kidney Function, Failed Transplant, Technique Survival, Diuresis
Complications in Planned vs. Unplanned Peritoneal Dialysis Starts
A metaanalysis of 14 papers totalling 2,401 PD patients looked at the outcomes and safety of unplanned PD starts within 7 days of catheter placement vs. 7-14 days. Early-start PD was linked with more leaks, omental wrap, and—for CAPD—catheter malposition. There were no significant differences in infectious complications, but the risk of transition to HD and mortality were higher. More studies are needed.
Read the abstract » | (added 2020-11-12)