C-reactive Protein to Albumin Ratio (CAR) on PD Predicts Survival

An analysis of 758 PD patients observed for up to 12 years found that those whose CAR was lower were significantly more likely to survive than those whose CAR was higher.

Read the abstract » | (added 2020-08-11)

Tags: Serum C reactive Protein To Albumin Ratio, Serum C reactive Protein, PD, Peritoneal Dialysis

Why Early Survival on PD Matters

If survival between PD and standard in-center HD “evens out in the end,” does it matter? Yes, argues Mark Marshall, MD, from New Zealand. The early survival benefit increases patient life years—and persists even when accounting for use of central venous HD catheters. To support shared decision-making, patients have the right to know about survival on PD vs. standard HD.

Read the abstract » | (added 2020-03-16)

Tags: Survival, PD, In center HD, Early Survival, HD Catheter

Survival with PD vs. Home HD and When to Go Home

Using a national cohort of 1,993 patients transitioning to home HD and 16,514 to PD between 2007 to 2011, 1,195 home HD were matched to 1,195 using propensity scores and adjusting for demographics, comorbidities, dialysis duration, and BMI. Those on home HD had significantly better survival (9.6 vs. 12.9 deaths per 100 patient-years; p<0.001). However, when patients switched to PD within the first 12 months of starting dialysis, survival was comparable between PD and home HD: patients who transitioned after 12 months had an 83% higher risk of death.

Read the abstract » | (added 2020-02-19)

Tags: Home HD, PD, Comorbidities, Dialysis Duration, BMI, Survival

PD vs. In-center HD for Sudden Cardiac Death

A Korean registry study of 132,083 PD and in-center HD patients followed between 1985 and 2017 analyzed 34,532 deaths. Sudden cardiac death (SCD) was responsible for 19.6% of deaths on PD and 22.2% of deaths on in-center HD. Even after adjusting for age and comorbidities, the risk of SCD was higher with HD.

Read the abstract » | (added 2020-01-09)

Tags: PD, In center HD, Sudden Cardiac Death

Home HD: Hospitalizations and Technique Survival

In a Swedish registry study, patients initiating PD (n=456), home HD (n=152), and in-center HD (IHD; n=608) were matched by age, sex, comorbidity, and start date. Patients using home HD had significantly lower hospital admissions and days than those doing PD or IHD (1.7, 12 days vs. 2.8, 20 days and 2.2, 14 days respectively). Home HD patients also had significantly fewer admissions for cardiovascular diagnoses or infectious disease, as well as significantly longer technique survival.

Read the abstract » | (added 2020-01-09)

Tags: PD, Home HD, In center HD, Hospital Admissions, Cardiovascular Diagnosis, Infectious Disease, Technique Survival

Factors Associated with Fatigue in PD Patients

Analysis of fatigue scale data from 108 PD patients in China revealed that 78.7% suffered from fatigue, a number significantly higher than in the community population. Associated factors included sleep quality, normalized protein nitrogen appearance, transferrin, alkaline phosphatase, and total cholesterol levels.

Read the abstract » | (added 2020-01-09)

Tags: Fatigue, PD, Sleep Quality, Protein Nitrogen Appearance, Transferrin, Alkaline Phosphatase, Total Cholesterol Levels

Diabetes and the Risk of Peritonitis on PD

In contrast to earlier reports, a single-center study of PD patients between 1980 and 2012 (by era: 1980-’93, 1994-’04, 2005-12) found that while PD-associated peritonitis was higher among patients with diabetes in the earlier two eras, there were no differences in recent years.

Read the abstract » | (added 2020-01-09)

Tags: PD, Peritonitis, Diabetes

PD—Controlling Volume to Reach Normal Hydration Protects the Heart

Reanalysis of data from a multicenter, prospective, randomized controlled trial looked at fluid control in PD in 151 patients followed for a year. While most (120) reached normal hydration levels as measured by bioimpedance analysis, those who did not had significantly higher left atrial diameter—and a lower left ventricular ejection fraction at the end of the study.

Read the abstract » | (added 2019-12-10)

Tags: Fluid Management, Cardiovascular Risk, PD, Peritoneal Dialysis, Bioimpedance Spectroscopy

Proton Pump Inhibitors Increase Peritonitis Risk in PD

In a single-center, 36-month retrospective look at 230 Japanese PD patients, those who took PPIs were 72% more likely to develop peritonitis than those who did not.

Read the abstract » | (added 2019-11-16)

Tags: PD, PPIs, Peritonitis, Proton Pump Inhibitors

Is PD Unwise for Patients with Lupus Nephritis?

A small study found 92.4% (1 year), 84.7% (3 year) and 67.6% (5 year) patient survival among 28 non-diabetic lupus patients doing PD—compared to 100% (1 year), 93.5% (3 year), and 82.9% (5 year) among 56 controls. While the lupus was not directly associated with mortality, it was a risk factor for PD technique failure, infection, and hospitalizations.

Read the abstract » | (added 2019-11-16)

Tags: Patient Survival, Lupus, PD, Mortality, Technique Failure, Infection, Hospitalization