Journal Watch - Dialysate

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  • 24-hour Dietary Recall Less Accurate for Protein Intake Assessment in PD

    Among 50 PD patients, use of protein nitrogen appearance (PNA) revealed levels of protein that ranged from 48.27-67.74 grams per day; median 55.75—while 24-hour dietary estimated the levels at 45.28-87.40; median 61.43 g/day. The authors suggest that proportionality bias may have influenced the results.

    Read the abstract » | (added 2020-10-12)

    Tags: Dialysis Initiation, Dialysate, Peritoneal Dialysis, PD

  • Impact of daily low-flow HD on potassium and lactate levels

    In the NxStage FREEDOM study, 345 patients switched from standard in-center HD to daily, low-flow HD. Blood levels of potassium and lactate were analyzed during the last 3 months of standard HD and the first 3 months of daily HD. On daily HD, predialysis serum potassium decreased significantly at a dialysate potassium level of 1 mEq/L, with no change at 2 mEq/L. Predialysis serum bicarbonate level decreased significantly with dialysate lactate concentration of 40 mEq/L—but increased significanty at 45 mEq/L. Choosing the correct dialysate for the patient is important.

    Read the abstract » | (added 2019-07-15)

    Tags: Daily HD, Potassium, Bicarbonate, Dialysate

  • MXene Sorbents: A Step Toward a WAK

    A sorbent tested for use in a wearable artificial kidney was able to adsorb urea with 99% efficiency in testing—twice the level removed with standard dialysate. The hemocompatible sorbent did not damage cells or reduce cell viability at the concentrations tested. A successful sorbent product will facilitate the design of a WAK. Read the abstract.

    Read the abstract » | (added 2018-10-12)

    Tags: Wearable Artificial Kidney, 2D Materials, Urea, MXene, Adsorption, Dialysate