Impact of daily low-flow HD on potassium and lactate levels

In the NxStage FREEDOM study, 345 patients switched from standard in-center HD to daily, low-flow HD. Blood levels of potassium and lactate were analyzed during the last 3 months of standard HD and the first 3 months of daily HD. On daily HD, predialysis serum potassium decreased significantly at a dialysate potassium level of 1 mEq/L, with no change at 2 mEq/L. Predialysis serum bicarbonate level decreased significantly with dialysate lactate concentration of 40 mEq/L—but increased significanty at 45 mEq/L. Choosing the correct dialysate for the patient is important.

Read the abstract » | (added 2019-07-15)

Tags: Daily HD, Potassium, Bicarbonate, Dialysate

Bioimpedance Assessment of Conventional vs. Daily HD

In a small physiological study, 12 patients were switched from conventional (3x/week) to daily (6x/week) HD treatments. Baseline and monthly blood pressure, BMI, and bioimpedance measurements were gathered on participants. Among the 9 patients who completed the data collection, body composition was not altered--but fluid overload was reduced and fewer antihypertensive medications were needed.

Read the abstract » | (added 2019-06-13)

Tags: Conventional HD, Daily HD, Blood Pressure, BMI, Bioimpedance, Fluid Overload, Antihypertensive Medications