Journal Watch

  1. Using Plant-Protectant Resveratrol to Preserve the Peritoneum

    Resveratrol is a phenol found in the skins of grapes and some berries that can help keep blood vessels from growing to support tumors. A new prospective, randomized, controlled, double blind study looked at its use to keep blood vessels from growing in the peritoneum, which can cause PD technique failure. Participants (n=72) were given 12 weeks of low- or high-dose resveratrol or placebo. Those who received a high dose of resveratrol had significantly better ultrafiltration.

    Read the abstract » | (added 01/10/2016)

    Tags:

  2. CT Scans Can Help Find Encapsulating Peritoneal Sclerosis

    Finding EPS early can make treatment of this devastating problem more successful. This study had experienced radiologists look at CT scan results from 18 people with confirmed EPS and 26 matched controls with it. The radiologists were blinded to who had the disorder. Peritoneal thickening, calcification, and other findings were more common in the EPS group. Some radiologists were better than others at detecting the differences that suggested EPS.

    Read the abstract » | (added 01/10/2016)

    Tags:

  3. Meta-Analysis: Longer Dialysis, Better Pregnancy Outcomes

    A new metaanlysis analyzed 190 papers and 25 abstracts covering 681 pregnancies in 647 women on dialysis. Meta-regression analysis found that more hours of HD per week was associated with a lower rate of preterm delivery, and that more dialysis sessions per week was associated with larger birthweight babies. Case reports suggested fewer small for gestational age babies with HD than with PD. No increased risk of birth defects was found.

    Read the abstract » | (added 12/10/2015)

    Tags:

  4. Home HD Has Shorter Recovery Time After Treatment Than In-Center HD

    A UK study asked 288 people “how long does it take for you to recover from an HD session?” Compared to a mean of 193 minutes (3+ hours) for the 197 people dialyzing in-center, the 91 home dialyzors had a mean of 67.3 minutes (just over an hour). While conventional home HD vs. intensive home HD had similar results, those who made more urine recovered faster.

    Read the abstract » | (added 12/10/2015)

    Tags:

  5. Buttonhole Cannulation Does NOT Raise Infection Risk—at Satellite

    AVF infection rates were examined among 162 patients from 1990 through 2012, which represents a changeover from rope ladder cannulation (1990-1998) to the Buttonhole technique (1998 onward). The difference in infection rates between the two techniques was not significant. Recurrence of AVF-infection was found only during time 2.

    Read the abstract » | (added 12/10/2015)

    Tags:

  6. Liraglutide Has Multiple Benefits in People with Diabetes on PD

    In a small study, injectable liraglutide was tested in 16 people with type 2 diabetes who use PD, 11 of whom were previously on insulin, while three used oral medications and two controlled their blood sugar using diet alone. After 12 months, glucose fluctuations were reduced, post-meal blood sugars were lower, systolic blood pressure dropped—and left ventricular mass decreased (on echocardiogram).

    Read the abstract » | (added 12/10/2015)

    Tags:

  7. Gentamycin Ointment For PD Exit Sites Did Not Increase Antibiotic Resistance

    A review compared 10 years PD exit-site care using oral rifampin and mupirocin ointment (n=265) with 10 years of gentamycin cream (n=179). While the demographics were largely similar apart from race, there were significantly fewer gram-negative exit site infections using gentamycin, with very low rates of gentamycin resistant infections in either period.

    Read the abstract » | (added 12/10/2015)

    Tags:

  8. RCT of Self-Locating PD Catheter Finds Fewer Flow Problems

    Coiled or straight, Tenckhoff catheters often clog. A new small trial randomized 61 people to receive a straight Tenckhoff (n=32) or a new, self-locating Wolfram PD catheter (n=29) for urgent start PD. Seven of the Tenckhoff’s had to be swapped for Wolframs due to flow issues—but the reverse was not true.

    Read the abstract » | (added 12/10/2015)

    Tags:

  9. Trial of a Virtual Home HD Ward

    Transitions from hospital stays back to home can lead to gaps in care. In Toronto, a virtual ward (VW) has been tested to see if care can be made more seamless. Following hospital discharge, a procedure, an antibiotic prescription, and/or completion of home dialysis training, patients were followed in the VW for 14 days. A nurse looked for the need for an HD prescription change, coordination of follow-up care, and medication changes. Care gaps were found in 67% of the 52 VW admissions for a total of 85 gaps. The researchers concluded that using a VW is practical, feasible, and identifies gaps that can be addressed.

    Read the abstract » | (added 11/11/2015)

    Tags:

  10. Case Report: Thrombocytopenia with NxStage

    Two patients have developed thrombocytopenia while using NxStage dialysis machines, perhaps due to electron-beam sterilization of the dialyzers. Switching to another machine resolved the problem; but it recurred in the patient who retried NxStage.

    Read the abstract » | (added 11/11/2015)

    Tags: