Journal Watch
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Pet Cats and Peritonitis—a Non-starter for PD?
The answer might surprise you. In a retrospective registry study in France, 52 PD patients who developed cat-related peritonitis were matched with 208 controls whose PD peritonitis was due to other causes. After analysis, pet-related peritonitis had lower risks of death or transfer to HD and a higher rate of transplant than other-cause peritonitis. The authors concluded that, while cats may cause peritonitis, having pets at home should not be considered a reason to refuse patients PD.
Read the abstract » | (added 2024-11-21)
Tags: Pets, Cats, Peritonitis, Pet related Peritonitis, PD, Technique Survival
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Stepwise PD Starts vs. Conventional PD Starts—Which is Better?
Stepwise Initiation of PD (SIPD) is an approach that uses a gradual introduction to PD (perhaps like incremental PD in the U.S.?). In a retrospective look at 39 SIPD patients vs. 78 conventional PD (CPD) starts during a 13-year period matched for age and sex, early complications and PD catheter survival were similar between groups. But, late complications were significantly lower in the SIPD group. The authors believe SIPD may aid tissue healing and reduce biofilms, which may reduce infections. As always, more studies are needed…
Read the abstract » | (added 2024-11-21)
Tags: Stepwise Initiation Of PD, Incremental PD, Late Complications, Infection, Tissue Healing, Biofilms
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Cloudy-only Peritonitis May Point to Vancomycin First
A study that looked at clinical characteristics of PD-associated peritonitis (PDAP) was able to correlate the signs and symptoms with the pathogen, allowing the team to choose antibiotics in a more informed way. The researchers divided the records of 162 patients with culture-positive PDAP into those who had cloudy effluent only vs. those who also had pain and/or fever, and compared the culture and sensitivity results. All 30 of the cloudy-only group had gram-positive infections; significantly more than the multi group (P<0.001), and 29 of those infections were susceptible to vancomycin, for specificity of 98.48%. This insight may help guide a first choice of antibiotic.
Read the abstract » | (added 2024-10-15)
Tags: PD associated Peritonitis, Cloudy Effluent, Vancomycin
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More Nephrologist Time Linked with Lower PD Peritonitis and Catheter Infection Rates
A PDOPPS study in Korea divided 276 incident PD patients into two groups based on whether they got <15 minutes (n=184;66.7%) vs. >15 (n=92; 33.3%) minutes of nephrologist time during each visit. Average age between groups did not differ, but the group that had more nephrologist time had significantly fewer 3- and 12-month PD-related infections.
Read the abstract » | (added 2024-10-15)
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CAPD vs. APD: Meta-analysis Sheds No New Light
A Cochrane Kidney and Transplant Register of Studies update identified two new randomized controlled trials (n=131) to include, one with 6-month follow-up and one with 24-month follow-up. Both studies had mostly low risk of bias. Conclusions about differences in CAPD and APD outcomes for death, hospitalizations, peritonitis, modality change, residual kidney function, health-related quality of life, overhydration, blood pressure, and a host of other outcomes were all based on low to very low certainty evidence.
Read the abstract » | (added 2024-10-15)
Tags: CAPD, APD, Modality Outcomes
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Utility of the 5-day Cell Count in Refractory Peritonitis
A retrospective study in Turkey analyzed 11 years of data on 135 patients with 236 episodes of refractory peritonitis. While age, gender, diabetes, prior hemodialysis, and PD duration did not reveal any significant differences, a day 5 dialysate white blood cell count higher than 1000/mm3 and hospitalization were linked width catheter loss.
Read the abstract » | (added 2024-10-15)
Tags: Refractory Peritonitis, Arteriovenous Fistula, Ark Implant, Cannulation
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Preferences for ESKD Treatment Options among Seniors
A choice experiment of 327 UK seniors (median age 77) with stage 4 CKD examined the survival benefit patients needed 2 years after starting treatment to accept dialysis. Overall, they needed 8-59% absolute survival benefit, and preferred less frequent treatment and home treatment. Seniors who had partners had significantly higher preferences for survival. Most wanted their capacity preserved and an acceptable frequency of care.
Read the abstract » | (added 2024-10-15)
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Updated ISPD Adequacy and Prescription Clinical Guidelines
PD adequacy is transitioning from solute clearance and ultrafiltration to quality of life. With sections on adequacy, residual kidney function, and prescription of CAPD and APD, the new guidelines specify the level of evidence and strength of the recommendations
Read the abstract » | (added 2024-10-15)
Tags: PD Adequacy, Solute Clearance, Ultrafiltration, Quality Of Life
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Potential Benefits for Tidal (TPD) vs. Intermittent PD (IPD)
A study randomized 85 patients to TPD (n=43) or IPD (n=42) and followed them for up to 2 years. Of the total, 19 patients died and 25 stopped PD. There were no differences in overall survival or technique survival among the remaining patients, but those who did TPD had significantly higher urine volume (p=0.001) as well as lower BUN (p=0.002) and phosphorus (p=0.004) and fewer cycler alarms (p<0.001). The TPD group had a higher chance of reporting abdominal fullness (p=0.001).
Read the abstract » | (added 2024-09-12)
Tags: Tidal PD, TPD, Intermittent PD, IPD
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Self-efficacy Support for Home Dialysis Patients
Data were extracted from 15 primarily quantitative studies of home dialysis training programs promoting self efficacy. Researchers identified that self-efficacy builds over time, with two themes that included gaining skills and building and maintaining knowledge. Multifaceted strategies and support from nurses, families, and peers helped patients develop self-efficacy around home dialysis.
Read the abstract » | (added 2024-09-12)