Journal Watch
Pathophysiology of Encapsulating Peritoneal Sclerosis (EPS)
EPS is a rare but often fatal complication of PD. Biopsy findings from Japan suggest that EPS is not sclerosis, but formation of a neo-membrane in response to a peritoneal injury.
Read the abstract » | (added 2023-06-14)
Tags: EPS, Sclerosis, Neo membrane
Portable, Wearable, and Implantable Artificial Kidneys
The need to continuously regenerate dialysate is a challenge for all portable, wearable, and implantable kidney replacement therapy options. Sorbent technology is one approach. New membrane materials can remove more uremic toxins than current ones. Combining these membranes with living kidney cells has potential as well.
Read the abstract » | (added 2023-06-14)
Tags: Dialysate, Portable, Wearable, Implantable Kidney, Kidney Replacement Therapy
Intraperitoneal Sodium Thiosulphate for Calciphylaxis in PD
Calciphylaxis, or extraskeletal calciphylaxis is a rare, life-threatening condition. In a case series, researchers demonstrated that intraperitoneal delivery of sodium thiosulphate was a safe, convenient, long-term alternative to IV therapy.
Read the abstract » | (added 2023-06-14)
Factors Linked with Time to First Peritonitis on PD
In a 5-year, 57 clinic, prospective randomized controlled trial in Europe, 33% of 671 participants had a bout of peritonitis. The factors independently linked with time to first peritonitis included older age, higher number of PD bags, low serum albumin, and higher body weight.
Read the abstract » | (added 2023-04-19)
Tags: Peritonitis, Age, PD Bags, Serum Albumin, Body Weight
Meta-analysis of PD Remote Patient Monitoring
Analysis of data from 22 studies revealed that remote monitoring for PD reduced technique failure, hospitalization, and mortality vs. traditional PD monitoring.
Read the abstract » | (added 2023-04-19)
Tags: Remote Monitoring, PD, Technique Failure, Hospitalization, Mortality, Traditional PD Monitoring
Significant Racial Disparities Remain in Home Dialysis
A retrospective cohort study looking at nearly 1.1 million ESKD patients between 2006 and 2016 found that while mean rates of home dialysis increased, white patients still had higher home dialysis use (26.2% in 2016) than non-white patients (17.8%), nor have the racial disparities improved over time.
Read the abstract » | (added 2023-04-19)
How Kidney Patients Define Health
Among people with kidney failure who used three or more treatment options, “health” was linked to the ability to take part in meaningful activities and maintain life balance. Social and treatment environments that supported autonomy also helped people to consider themselves healthy.
Read the abstract » | (added 2023-04-19)
Tags: CKD, Treatment Options, Health, Treatment Experience, Shared Decision making
Nephrologist Attitudes Toward Home Therapies Drive Practice
A survey of 327 nephrologists assessed their knowledge, attitudes, and practice around the choices for renal replacement therapy. Attitudes toward PD, HD, and transplant were independently linked to participants’ consideration of these options for patients.
Read the abstract » | (added 2023-04-19)
Tags: Nephrologists Modality Knowledge, Modality Bias, Choices For Renal Replacement Therapy, Modality Choice, Patient Education, Shared Decision making
The Impact of Patient Empowerment on PD Self-management
A controlled trial investigated use of a problem-based learning (PBL) model to empower people on PD to self-manage. Among 94 participants, 47 patients were randomized to PBL learning, while the control group got usual care. PBL participants were divided into five study groups that each had six lessons. After 9-11.5 months, the PBL group had significantly more basic PD knowledge, higher self-management scores, better quality of life, increased satisfaction, and less depression and anxiety.
Read the abstract » | (added 2023-04-19)
Tags: Problem based Learning Model, PBL, Self management, PD Knowledge, Quality Of Life, Depression, Anxiety
Serum Phosphorus and Survival on PD
Data from 5,847 PD patients between 2014-2017 from seven countries in the PDOPPS study found that compared to an optimal range of 3.5-4.5mg/dL, the hazard ratio (HR) for all-cause mortality was 19% higher when phosphorus was 5.5-6.5 and 53% higher when phosphorus was greater than 6.5. When 6 months of data were examined, the linkage was even stronger.
Read the abstract » | (added 2023-02-13)
Tags: PD, Serum Phosphorus, PDOPPS, Hazard Ratio, All cause Mortality