Journal Watch - PD Dialysate
How Glucose Causes Peritoneal Fibrosis
Constant glucose exposure from PD dialysate often causes fibrosis that can make further PD impossible. High glucose causes chronic inflammation, interferes with lipid metabolism, and leads to angiogenesis and fibrosis. RAAS activation contributes to this process as well. There may be benefit to looking at the upstream pathways to see if there are ways to block fibrosis.
Read the abstract » | (added 2023-08-16)