How Glucose Causes Peritoneal Fibrosis

Constant glucose exposure from PD dialysate often causes fibrosis that can make further PD impossible. High glucose causes chronic inflammation, interferes with lipid metabolism, and leads to angiogenesis and fibrosis. RAAS activation contributes to this process as well. There may be benefit to looking at the upstream pathways to see if there are ways to block fibrosis.

Read the abstract » | (added 2023-08-16)

Tags: High Glucose, PD Dialysate, Fibrosis