Zinc Deficiency and Anemia in PD

Analysis of data from 164 adults on PD set a target hemoglobin level of 11-13g/dL and ESA dosage as low- (<120 µg/month) or high-dose (>120 µg/month). Zinc deficiency was defined as a serum zinc level <60 µg/dL. In the low-dose ESA, non-zinc deficient group, 48.2% of patients achieved the target hemoglobin level, while in in the high-dose ESA, zinc-deficient group, just 12.2% did. These results were not changed with the addition of serum albumin C-reactive protein, or TSAT. The authors conclude that “serum zinc levels should be routinely monitored in patients with ESA-hyporesponsive anemia.”

Read the abstract » | (added 02-17-2026)