Risks of biocompatible PD solution
Sugar (dextrose) in PD solution helps remove water from the blood—at a cost. Advanced glycation endpoints (AGEs) formed when the solution is made can harm the peritoneum over time. It would seem to make sense more biocompatible (like the human body) solutions would be better and safer. Some studies have found this, but a new look in the ANZDATA registry of all PD patients from Australia/New Zealand from January 1, 2007 and December 31, 2010 did not. Use of biocompatible PD solution was linked with significantly more (49% more) peritonitis, and far less time to a first bout of the infection.
Read the abstract » | (added 10-02-2013)