HOW do AGE’s Cause Peritoneal Fibrosis?

For years, researchers have known that the advanced glycation endpoints (AGEs) that form when sugar-based PD fluid is made harm the membrane. But, we didn’t know why. Human cell modeling finds that AGEs cause outer layer peritoneal cells (epithelial) to become connective tissue cells (mesenchymal).

Read the abstract » | (added 2019-03-12)

Tags: AGEs, Mesothelial, Epithelial, STAT3