Mineral Bone Disease (MBD) and Survival on PD

A P-DOPPS study analyzed MBD data from more than 12,000 patients from eight countries. The results revealed a U-shaped curve for the relationship between PTH and mortality, with the lowest risk at PTH levels of 300-599 pg/mL. Serum calcium levels higher than 9.6 mg/dL were associated with a 20% increase in mortality as well. Major country variations in MBD treatment were identified.

Read the abstract » | (added 2024-04-12)

Tags: Mineral Bone Disease, MBD, PTH, Mortality, Serum Calcium Levels, PD

New Nomogram Predicts Roxadustat Treatment Failure in Anemic PD Patients

A retrospective analysis of 204 anemic PD patients from 2019 to 2023 was used to construct a predictive nomogram of Roxadustat success. Duration of PD, serum transferrin, cardiovascular comorbidities and stains were significant predictors. The nomogram was more predictive at 12 months than at 6 months.

Read the abstract » | (added 2024-04-12)

Tags: Roxadustat, HIF inhibitor, Treatment Failure, Anemia, PD

Comprehensive Health Education and PD

Among 98 PD patients randomly assigned to routine care or a full-course health education program, the full-course group had significantly higher health behavior and treatment adherence scores. They were more likely to take their medications correctly and had better quality of life and fewer hospital readmission rates than controls.

Read the abstract » | (added 2024-04-12)

Tags: Peritoneal Dialysis, PD, Comprehensive Health Education, Education Program, Quality Of Life

Impact of Prior Abdominal Procedures on Peritoneal Dialysis Catheter Outcomes: Findings From the North American Peritoneal Dialysis Catheter Registry

A history of prior abdominal procedures may influence the likelihood of referral for peritoneal dialysis (PD) catheter insertion. To guide clinical decision making in this population, this study examined the association between prior abdominal procedures and outcomes in patients undergoing PD catheter insertion.

Read the abstract » | (added 2024-03-15)

Tags: Dialysis, PD, PD Catheter Outcomes, End Stage Kidney Disease, Peritoneal Dialysis, Prior Abdominal Surgery

A Home Dialysis Primer for Internists

A new primer developed for clinicians in primary care aims to explain PD and home HD.

Read the abstract » | (added 2024-02-07)

Tags: Home Dialysis Primer, PD, Home HD

Progression of Brain Atrophy in PD vs. HD

A follow-up study of brain atrophy progression followed 73 PD and 34 HD patients who had brain MRIs, including 42 PD and 25 HD patients who had a second brain MRI. Brain grey matter volume measurement demonstrated faster progression of brain atrophy in PD than in HD, independent of potential confounders.

Read the abstract » | (added 2024-01-17)

Tags: Brain Atrophy, PD, HD

Among Prediabetic Patients, PD Nearly Tripled the Risk of New Onset Diabetes vs. HS

A retrospective cohort study was done of 1426 non-diabetic end-stage renal disease (ESRD) patients who started PD or in-center HD. Over a 12 year period, 23% of the patients developed NODM. Among patients with prediabetes, those on PD had a 2.93 times higher risk of NODM than those on HD (p <0.001).

Read the abstract » | (added 2024-01-17)

Tags: ESRD, PD, In center HD, NODM, New Onset Diabetes Mellitus

A Home Dialysis Primer for Internists

Since PD and home HD are increasing in use due to their clinical and practical advantages, clinicians need to understand these treatments. A new primer in the Annual Review of Medicine will help them do just that.

Read the abstract » | (added 2023-12-15)

Tags: Home Dialysis, HD, PD, Home Dialysis Primer

Dietary Protein Intake and Survival on PD

Among 668 stable PD patients followed for up to 13 years, quarterly 3-day dietary records were collected for 2 ½ years. Dietary protein intake greater than 0.8 g/Kg/day improved long-term survival.

Read the abstract » | (added 2023-12-15)

Tags: Dietary Protein, Survival, PD

GI Outcomes in PD Trials

A meta-analysis of 61 trials looking at patient-reported GI outcomes of PD mainly found nausea (43% of trials), diarrhea (43%), constipation (34%), abdominal pain (31%) and PD peritonitis (40%). But, only 19% of the available trials reported GI outcomes at all.

Read the abstract » | (added 2023-07-17)

Tags: GI Outcomes, PD, Nausea, Diarrhea, Constipation, Abdominal Pain, Peritonitis