HD Adequacy Based on Middle Molecules

A crossover study of 30 HD patients assessed middle molecule removal with standard HD vs. hemodiafiltration (HDF), with a 2-week washout period between them. Measurements of serum IL-1 and myoglobulin were measured pre- and post-treatment. There were no differences in these levels at baseline, and the highest reduction ratios for both IL-1 (81.6+12.6%) and myoglobulin (83.8+10.6%) as well as urea (75.2+5.6%) were found after HDF.

Read the abstract » | (added 2026-01-16)

Tags: HD Adequacy, Middle Molecules, IL 1, Myoglobulin