PD Peritonitis and the Gut Microbiome

Researchers investigated a causal relationship between the gut microbiome and peritonitisby combining Mendelian randomization of statistics from genome-wide association studies (GWAS) and a case control study of 24 patients. The results suggested potential destabilization of the gut bacterial network in patients with peritonitis. In particular, there were significant negative correlations between interleukin-6 levels and Faecalibacterium, Coprococcus, Dorea, Anaerostipes, and Lachnospira.

Read the abstract » | (added 2025-08-21)

Tags: Mendelian Randomization, Peritoneal Dialysis associated Peritonitis, Amplicon Sequencing, Cytokine, Gut Microbiome