Journal Watch

« Back to Most Recent

  • Protect the peritoneal membrane to do PD longer

    A new review article suggests replacing some glucose-based dialysate exchanges with icodextrin, resting the peritoneum, using bicarbonate or pyruvate as a buffer, and treating infections immediately as ways to help protect the peritoneal membrane.

    Read the abstract » | (added 2011-02-24)

    Tags:

  • Meta-analysis: Icodextrin PD fluid really does have advantages

    In a study of 9 randomized controlled trials, icodextrin removed much more water from the blood of people who did PD than standard glucose-based PD fluid without causing any more health problems for them.

    Read the abstract » | (added 2011-02-24)

    Tags:

  • Icodextrin improved nutrition and inflammation in PD

    Replacing glucose-based PD fluid with icodextrin led to 66% better fluid removal, significantly higher protein levels, and significantly lower levels of the inflammation marker CRP.

    Read the abstract » | (added 2011-02-24)

    Tags:

  • Icodextrin PD fluid causes less weight gain

    We're not surprised to learn that PD fluid that doesn't contain dextrose (sugar) is less likely to cause weight gain! A study of 183 PD patients found weight gains after 3 years (88% of it fat) among those using standard fluid, and significantly less weight gain in an icodextrin group.

    Read the abstract » | (added 2011-02-24)

    Tags:

  • Diabetes + PD? Icodextrin-aided fluid removal and metabolic control

    A randomized controlled trial of glucose PD fluid vs. icodextrin (ICO) found significant benefits. Among 59 people with diabetes on CAPD, those in the group using ICO for the long exchange were far less likely to need higher concentration fluid (9% vs. 66%). And, the ICO group needed less insulin, had lower triglycerides, and had lower A1cs.

    Read the abstract » | (added 2011-02-24)

    Tags:

  • Does icodextrin (extraneal) cause more peritonitis?

    Doesn't look like it. A study observed icodextrin and regular, sugar-based PD fluid use in 722 people. No differences were found in the rate of peritonitis infection or so-called "sterile periotnitis" where no bacteria are found.

    Read the abstract » | (added 2011-02-24)

    Tags: