Journal Watch

  • Serum Uric Acid and Residual Kidney Function in PD

    In a study of 201 CAPD patients followed for up to 8 years (median 23.43+ 16.6 months), high or low serum uric acid and peritonitis were independent risk factors for loss of all residual kidney function. Higher weekly Kt/V urea helped protect residual function.

    Read the abstract » | (added 2020-08-11)

  • Quanta SC+ Fluid Removal Accuracy

    Through both passive and active fluid control mechanisms, the Quanta SC+ home HD machine was accurate to within 1 mL per hour for flow balance and to within 13 mL/hr for ultrafiltration.

    Read the abstract » | (added 2020-08-11)

  • Carnitine Deficiency and ESA Resistance in PD

    Among 60 PD patients, 56 had carnitine deficiency, which was found to independently predict ESA resistance.

    Read the abstract » | (added 2020-08-11)

  • Case Report: Intensive Daily HD Improves Lung Function

    After initiating 32 hours of intensive home HD per week, a patient with restrictive lung disease had improvement in both clinical and spirometric lung function.

    Read the abstract » | (added 2020-08-11)

  • C-reactive Protein to Albumin Ratio (CAR) on PD Predicts Survival

    An analysis of 758 PD patients observed for up to 12 years found that those whose CAR was lower were significantly more likely to survive than those whose CAR was higher.

    Read the abstract » | (added 2020-08-11)

  • Home HD Respite Care Resource Implications

    A Canadian analysis of 119 home HD patients found that 66% required 292 back-up, in-center HD sessions during 96 patient years; 53% for vascular access issues.

    Read the abstract » | (added 2020-08-11)

  • How Much Dialysate Should be Used for Nocturnal HD With NxStage?

    Predictive modeling finds that the dialysate lactate concentration used for short daily HD may not be appropriate for nocturnal HD. Since the effect of lactate mainly depends on weekly dialysate volume, reducing from 60 to 30 liters for frequent nocturnal HD may be appropriate.

    Read the abstract » | (added 2020-08-11)

  • Starting with PD Better than Switching to it from HD

    A metaanalysis comparing patients who started with PD to those who began HD and then switched to PD after 3 months found significantly better overall and technique survival in the PD first group. There were no significant differences in the peritonitis rate.

    Read the abstract » | (added 2020-07-10)

  • PD Probiotics, Malnutrition, and Health-related Quality of Life

    In a controlled trial that randomized 116 PD patients into a probiotic and a control group, 2 months of probiotics reduced inflammation markers (HS-CRP and IL-6), and significantly improved serum albumin, upper arm circumference, and triceps skinfold thickness. The probiotic group also had higher physical and social functioning scores.

    Read the abstract » | (added 2020-07-10)

  • Dialysis Adequacy Predicts Sexual Function

    A study comparing men and women doing HD (n=70) or PD (n=57) to healthy male (n=65) and female (n=48) volunteers assessed sexual function, depression, anxiety, and health-related quality of life. In men, dialysis adequacy was the most important factor in sexual function. In women, dialysis adequacy and depression were both significant. Inadequate dialysis worsened sexual function and was associated with more anxiety and depression, and—in men—reduced health-related quality of life.

    Read the abstract » | (added 2020-07-10)