Journal Watch
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PD fluid with amino acids may help prevent malnutrition—and improve heart health
Basing PD fluid on amino acids (AA') instead of glucose may improve nutrition on PD in the future. A new study switched 13 non-diabetic PD patients from glucose to AA-based fluid. Uptake of amino acids by the skeletal muscles was significantly better with the AA fluid (read more here). Another study of AA-based PD fluid found it less likely than glucose-based fluid to cause release of hormones (leptin and adipnectin) linked with heart problems.
Read the abstract » | (added 02/24/2011)
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November 2006 Kidney International supplement focuses on PD
Is survival better on PD or HD? What factors predict PD success? What are best practices in PD catheter placement? Does use of biocompatible PD solution reduce peritonitis? Learn the answers to these and many other key PD questions in the November 2006 supplement of KI. (For kidney professionals who don't subscribe to Kidney International, we've compiled the links to all of the abstracts from the special supplement on PD (November 2006). You can find them below.
- Mortality studies comparing PD and HD: What do they tell us?
- French PD registry (RDPLF): Outline and main results
- PD in the US: Evaluation of outcomes in contemporary cohorts
- Selected best demonstrated practices in PD access
- Use of the embedded PD catheter: Experience and results from a North American Center
- Prevention of infectious complications in PD: Best demonstrated practices
- Microbiology and outcomes of peritonitis in North America
- Impact of new dialysis solutions on peritonitis rates
- Place of PD in the management of treatment-resistant congestive heart failure
- The role of PD in the management of treatment-resistant congestive heart failure: A European perspective
- Mitigating peritoneal membrane characteristics in modern PD therapy
- Profiles of automated PD prescriptions in the US 1997-2003
- Tidal PD: Its role in the current practice of PD
- The role of tidal PD in modern practice: A European perspective
- Glucose sparing in PD: Implications and metrics
- New insight of amino-acid based dialysis solutions
- Management of hyperlipidemia in patients on PD: Current approaches
- Structural requirements for a successful PD program
- Nosogogy: When the learner is a patient with chronic renal failure
- Patient retraining in PD: Why and when it is needed
- Patient and technique survival on peritoneal dialysis in patients with failed renal allograft: A case-control study
- Place of genotyping and phenotyping in understanding and potentially modifying outcomes in PD patients
Read the abstract » | (added 02/24/2011)
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Protect the peritoneal membrane to do PD longer
A new review article suggests replacing some glucose-based dialysate exchanges with icodextrin, resting the peritoneum, using bicarbonate or pyruvate as a buffer, and treating infections immediately as ways to help protect the peritoneal membrane.
Read the abstract » | (added 02/24/2011)
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C-reactive protein may help identify those at greater risk of post-peritonitis problems
People with higher CRP levels during and after peritonitis were at higher risk for relapse, a switch to HD, or death than those with lower levels, found a study in the Feb. 14 issue of Kidney International. CRP levels may be a useful screening tool.
Read the abstract » | (added 02/24/2011)
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Author suggests PD for disaster preparedness
A new article in this month's Advances in Chronic Kidney Disease suggests that PD is a good option for people whose dialysis lives are disrupted by hurricanes or other natural disasters. Home dialysis with PD, portable HD, or HD machines that do their own water treatment can help make dialyzors more self-sufficient in any emergency—from a storm to a flu epidemic. It's something to think about...
Read the abstract » | (added 02/24/2011)
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CAPD and CCPD come out even in meta-analysis
A Cochrane database review looked at studies comparing CAPD and CCPD for peritonitis, hernias, switching to HD, fluid leaks, hospital stays, and death—and found no significant differences between them. CCPD may have some pluses in terms of schedule for younger, working patients.
Read the abstract » | (added 02/24/2011)
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Low serum albumin is a risk factor for peritonitis in PD patients
On PD? Be sure to eat enough protein. A new study looked at whether conventional PD solutions were linked to more or less peritonitis than Nutrineal or Extraneal. There were no significant differences between them—but patients with serum albumin levels less than 3 g/dL were at significantly higher risk.
Read the abstract » | (added 02/24/2011)
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Make your own PD fluid?
Okay, it's a long way off. But what if you could make pure water at home for PD, instead of having to ship bags of PD fluid across the country? Think of the space you'd save. Researchers in Italy used a dialyzer to purify used PD fluid and create pure water.
Read the abstract » | (added 02/24/2011)
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Peritoneal cell transplants—a future option for PD?
Over time, glucose-based PD fluid can cause fibrosis and blood vessel changes to the peritoneal membrane, making PD impossible. But what if you could transplant the cells lining the peritoneum and grow a new layer from your own tissue? Could PD continue? Researchers are looking into this intriguing possibility.
Read the abstract » | (added 02/24/2011)
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Inflammation helps explain EPO resistance on PD
Sometimes high doses of EPO are needed to reach a target hemoglobin. Why? A new study found that on PD, inflammation (measured by c-reactive protein), too-low levels of serum albumin, and abnormal levels of PTH were some of the factors.
Read the abstract » | (added 02/24/2011)
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