Journal Watch - Chronic kidney disease
Mucomyst does not prevent nephrogenic systemic sclerosis
A new study randomized 2,308 people at risk for kidney injury from contrast dye into two groups. One group was given acetylcysteine (Mucomyst®) by mouth, a strong antioxidant. The other group was given a placebo. Both groups had the same rate of kidney injury and need for dialysis.
Read the abstract » | (added 2011-09-29)
Tags: Chronic kidney disease
The frontier of regenerative medicine—what it can mean for kidney disease
While dialysis can remove wastes and excess water from the blood, it can't replace or respond to hormones like healthy kidneys do. Regenerative medicine is at the cutting edge of efforts to grow kidney cells in the lab—with the goal of one day growing new kidneys. And, that day may not be far off.
Read the abstract » | (added 2011-07-26)
Tags: Chronic kidney disease
Ratios of Omega-6 to Omega-3 fats may impact health in kidney disease
Western diets tend to have too much omega 6 and not enough omega 3 fatty acids. In 145 people on standard in-center HD, having too much omega 6 was linked with significantly higher inflammation.
Read the abstract » | (added 2011-07-26)
Tags: Chronic kidney disease
CKD education rates in Australia (they're FAR better than in the US!)
It's hard to choose a treatment option for kidney failure that fits your life when you don't know what the options are, or how they might affect you. A study of 721 people new to dialysis in Australia found that 603 (84%) had options education before they started treatment.
Read the abstract » | (added 2011-05-23)
Tags: Chronic kidney disease
New model using routine lab tests can predict progression to kidney failure
Researchers looked at data from a total of 8,391 people with stages 3–5 CKD to see if lab test results could predict who would progress to end-stage. A model that included age, sex, GFR, and protein in the urine worked best.
Read the abstract » | (added 2011-05-23)
Tags: Chronic kidney disease
Oral adsorbents may help reduce levels of uremic toxins
The colon makes some wastes that are removed by the kidneys. So, drugs that keep these wastes from getting into the bloodstream could help keep them from building up in the body when the kidneys fail.
Read the abstract » | (added 2011-04-25)
Tags: Chronic kidney disease
Chemical ablation to correct recurrent secondary hyperparathyroidism post parathyroidectomy
Reoperation after a parathyroidectmy can be risky. In a study of 49 people, injecting ethanol (alcohol) into the gland, guided by ultrasound, helped to lower PTH levels without more surgery.
Read the abstract » | (added 2011-04-25)
Tags: Chronic kidney disease
Need high doses of EPO? Might want to check for CMV
A new study from the Netherlands has found that people who have ESRD and have been exposed to the cytomegalovirus (CMV) have immune changes. With fewer working T-cells, they can't respond as well to anemia drugs.
Read the abstract » | (added 2011-02-24)
Tags: Chronic kidney disease
People want treatments that offer FREEDOM
A new study interviewed 52 people who were on one of 4 types of dialysis or had a transplant—and learned that "freedom, convenience, self-care, effectiveness, and simplicity" were important. (We could have told you that.)
Read the abstract » | (added 2011-02-24)
Tags: Chronic kidney disease
Better CKD care saves lives
People who met targets for access, hemoglobin, and blood protein levels before starting dialysis were far more likely to survive the first year, finds a new study of 192,307 patients. But just 2% met all three goals—even when they'd been seeing a nephrologist for a year.
Read the abstract » | (added 2011-02-24)
Tags: Chronic kidney disease