NxStage Medical, Inc.

Did you know? Now you may be able to perform home hemodialysis at night while you sleep.

Did you know? Now you may be able to perform home hemodialysis at night while you sleep.

NxStage's® System One™ is the first and only hemodialysis machine cleared to perform home hemodialysis overnight while you sleep, known as home nocturnal hemodialysis. Nocturnal therapy is an important therapy option associated with a number of lifestyle and clinical advantages. By doing therapy while you sleep, you free up your day to pursue other activities and spend more time being you.

Watch how nocturnal therapy has changed Robby’s life »

Robby Richardson Video

“I don’t like to use term “quality of life” but I honestly never thought I could feel as well as I do again. My life literally went from spending all my spare time on the couch with video games to going back out into the world and being a part of it again.”

NxStage dialyzor - Robby R.

Robby performs home nocturnal hemodialysis six times a week.
Watch »

The clinical benefits associated with home nocturnal hemodialysis provide you the opportunity to live longer, celebrate more birthdays and experience more of what life can offer.

Benefits include:

Talk to your doctor to see if home nocturnal hemodialysis with NxStage is right for you.


Despite the health benefits that more frequent home hemodialysis may provide to those with chronic kidney disease, this form of therapy is not for everyone. Home hemodialysis with the NxStage System One requires a patient and partner who are committed to being trained on and following the guidelines for proper system operation.

The reported benefits of home hemodialysis may not be experienced by all patients.

The NxStage System One is a prescription device and, like all medical devices, involves some risks. The risks associated with hemodialysis treatments in any environment include, but are not limited to, high blood pressure, fluid overload, low blood pressure, heart-related issues, and vascular access complications. The medical devices used in hemodialysis therapies may add additional risks including air entering the bloodstream, and blood loss due to clotting or accidental disconnection of the blood tubing set. Patients should consult with their doctor to understand the risks and responsibilities of home and/or more frequent hemodialysis using the NxStage System One.

Certain risks are unique to the home. Treatments at home are done without the presence of medical personnel and on-site technical support. Patients and their partners must be trained on what to do and how to get medical or technical help if needed.

Certain risks associated with hemodialysis treatment are increased when performing nocturnal therapy due to the length of treatment time and because therapy is performed while the patient and care partner are sleeping. These risks include, but are not limited to, blood access disconnects and blood loss during sleep, blood clotting due to slower blood flow or increased treatment time or both, and delayed response to alarms when waking from sleep. Patients should consult with their physician to understand the risks and responsibilities associated with home nocturnal hemodialysis using the NxStage System One.


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3 Pierratos, A. Daily (quotidian) nocturnal home hemodialysis: Nine years later. s.l. : Hem Int, 2004. pp. 45-50. Vol. 8.
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5 Culleton BF, Walsh M, Klarenbach SW, Mortis G, Scott-Douglas N, Quinn RR, Tonelli M, Donnelly S, Friedrich MG, Kumar A, Mahallati H, Hemmelgarn BR, Manns BJ. Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life. JAMA. September 2007; Vol 298, No. 11, 1291 – 1299.

This article was posted on December 18th, 2015