Journal Watch - Reactive

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  1. Protein Clearance Predicts Mortality on PD

    Protein clearance on PD may be a marker of peritoneal inflammation. Among 711 PD patients followed for at least one year, each 10mL/day rise in protein clearance was linked with a 10.4% increase in the risk of all-cause mortality (p=0.008). Protein clearance was linked with serum albumin and C-reactive protein levels.

    Read the abstract » | (added 12/14/2018)

    Tags: Protein Clearance, Peritoneal Dialysis, Mortality

  2. PD After Loss of Residual Kidney Failure

    Once residual kidney function is gone, it is vital to address fluid volume, finds a new study that followed 183 people. During the 10.5-36 months of follow up, 65% either switched to HD or died. Their inflammation rates (measured by C-reactive protein levels) were high, as were their extracellular water levels (measured by bioelectrical impedance analysis).

    Read the abstract » | (added 01/10/2016)


  3. CRP levels and abdominal CT scans can find EPS early

    A look back at CT scans and c-reactive protein levels from 30 people diagnosed with encapsulating peritoneal sclerosis has provided clues for early diagnosis. Higher than normal levels of c-reactive protein plus abnormal CT scan results found the rare complication early 78% to 87% of the time—making effective treatment more possible.

    Read the abstract » | (added 09/11/2015)


  4. Men on PD fare worse with high serum uric acid levels

    In a study of 985 people using PD in China followed for more than 2 years, men in the highest tertile for serum uric acid were at the highest risk of death. The results were adjusted for age; BMI; comorbidities; residual kidney function; total Kt/V; use of allopurinol, ACE-inhibitors and ARBs; Hgb, serum albumin, creatinine, calcium and phosphorus, triglycerides, LDL cholesterol, and high-sensitivity C-reactive protein.

    Read the abstract » | (added 09/05/2014)


  5. Inflammation in PD? Look to the gums!

    Researchers looked at gum disease in 68 people who were doing CAPD, and rated it as healthy, slight to moderate, and severe. Patients whose C-reactive protein levels (a marker of inflammation) were higher had worse gum disease and had been on PD longer. Those with heart disease and diabetes also had worse gum disease. The authors suggest that all people who use PD should have their gums checked.

    Read the abstract » | (added 06/05/2014)


  6. High-sensitivity CRP levels predict technique and patient survival on PD

    High C-reactive protein (CRP) levels suggest inflammation. Among 402 PD patients followed for 2 years, those with the lowest CRP levels were more likely to still be on PD and had better survival. Each 1 mg/L increase in CRP predicted a 1.4% higher risk of mortality.

    Read the abstract » | (added 04/09/2014)


  7. More HD lowers C-reactive protein and boosts nutritional status

    A study from Iran found that adding one standard HD treatment per week for 6 weeks significantly decreased C-reactive protein (a measure of inflammation), and increased serum albumin and BMI. The authors conclude that getting more HD may reduce the risk of cardiovascular events.

    Read the abstract » | (added 04/29/2013)


  8. To reduce inflammation: Get rid of your HD catheter

    Even with no infection, an HD catheter can still trigger inflammation. In a new study, people who got a fistula and had a catheter removed had an 82% lower c-reactive protein (CRP) level 6 months later. Those who kept the catheter had a 16% higher CRP.

    Read the abstract » | (added 02/24/2011)


  9. Predicting blood vessel calcification in PD

    In a study of 231 PD patients, those whose C-reactive protein (CRP) and interleukin-6 levels were higher had a higher risk of blood vessel calcification and heart problems than those with lower levels.

    Read the abstract » | (added 02/24/2011)


  10. C-reactive protein may help identify those at greater risk of post-peritonitis problems

    People with higher CRP levels during and after peritonitis were at higher risk for relapse, a switch to HD, or death than those with lower levels, found a study in the Feb. 14 issue of Kidney International. CRP levels may be a useful screening tool.

    Read the abstract » | (added 02/24/2011)