Journal Watch - Phosphate

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  1. First European Patients Using Nocturnal Home HD with Low-flow Dialysate

    A retrospective analysis looked at 21 patients using low-flow dialysate for nocturnal home HD and followed for a minimum of 12 months. Participants had a mean dialysis duration of 28 hours per week; most used alternate nights and 50-60 L of dialysate per session. Use of phosphate binders and blood pressure medications was significantly reduced, and no patient safety events were reported.

    Read the abstract » | (added 01/09/2020)

    Tags: Low Flow Dialysate, Nocturnal Home Hd, Phosphate Binders, Blood Pressure Medication

  2. How longer HD treatments affect bone minerals

    The ACTIVE study randomized 200 people to do 24+ hours of HD per week vs. standard (<18 hours per week) HD. Long HD treatments reduced serum phosphate levels, but did not change PTH or serum calcium. In a second analysis of the data, those who did longer HD needed fewer phosphate binders as well.

    Read the abstract » | (added 07/15/2019)

    Tags: Hd Duration, Long Hd Treatment, Serum Phospate, Mineral Metabolism, Phosphate Binders

  3. New Model Could Help Screen PD Patients for CeVD Risk

    A new risk score could predict how likely new PD patients are to develop cerebrovascular disease down the road. The strongest predictors of CeVD were blood pressure, total cholesterol, and serum phosphate and sodium levels.

    Read the abstract » | (added 08/13/2018)

    Tags: Cerebrovascular Diseases, Mortality, Peritoneal Dialysis, Risk Prediction

  4. A Randomized, Controlled Trial of Instant Messaging for PD Patients

    Among 160 PD patients, the half assigned to instant messenger had significantly higher levels of satisfaction, serum albumin, and hemoglobin—and lower levels of serum phosphorus and calcium-phosphate product than controls.

    Read the abstract » | (added 05/11/2018)

    Tags: Instant Messaging Follow Ups, Peritoneal Dialysis

  5. Nocturnal Home HD Boosts Patient Employment Compared to PD

    A year-long study comparing 20 alternate-night nocturnal home hemodialysis patients to matched 81 CAPD patients in Hong Kong found 80% employment among the nocturnal HD patients (who were 5 years younger) and just 33.3% among PD patients. The nocturnal patients also used fewer phosphate binders. Read the abstract.

    Read the abstract » | (added 11/13/2017)

    Tags: Chinese, Nocturnal Hemodialysis, Employment Rate, Incident, Peritoneal Dialysis

  6. Iron-based Binder Safe and Effective in PD

    A study conducted with 84 PD patients compared sucroferric oxyhydroxide (n=56) to sevelamer (n=28). After a year, both groups had serum phosphate levels within the target range. The iron-based binder required fewer pills per day and resulted in fewer adverse events. Read the abstract.

    Read the abstract » | (added 11/13/2017)

    Tags: Chronic Kidney Disease, Hemodialysis, Peritoneal Dialysis; Phosphate Binder, Sevelamer Carbonate, Sucroferric Oxyhydroxide

  7. In-center Nocturnal HD Beats Standard HD

    An analysis of 21 published studies (n=1,165 in-center nocturnal patients and 15,865 standard in-center HD patients) found better BP, higher Hgb, and lower serum phosphate levels in those who dialyzed longer.

    Read the abstract » | (added 04/12/2017)

    Tags: Hemodialysis

  8. Magnesium and Vascular Calcification in PD

    In vitro and in animals, serum magnesium inhibits vascular calcification. In a study of 80 people on PD, X-ray studies of the spine found that the lower the serum magnesium levels, the higher the rate of calcification in the blood vessels. Adjusting for age, serum phosphate, serum PTH, cholesterol levels, smoking history, and diabetes did not change the results.

    Read the abstract » | (added 04/12/2017)

    Tags: Https://Www.Ncbi.Nlm.Nih.Gov/Pubmed/28385153

  9. Does Frequent HD Boost Quality of Life? NO

    A new Canadian study randomized 200 patients to standard in-center HD (12-15 hours/wk; maximum of 18 hours) or extended HD (>24 hours/wk) for a year. Extended HD reduced phosphate and potassium levels and boosted Hgb, and patients took fewer BP meds and phosphate binders. However, health-related quality of life scores did not differ significantly between the groups.

    Read the abstract » | (added 02/08/2017)

    Tags: Hemodialysis

  10. For HD Survival, Home Beats In-Center

    An observational study looked back at 41 incident patients starting home HD and matched them to patients starting in-center HD by sex, age, comorbidity, and start date. Mean survival on home HD was 17.3 years, vs. 13 years in-center. Home HD patients also had significantly lower phosphate levels and did not require blood pressure medications.

    Read the abstract » | (added 07/12/2016)

    Tags: Hemodialysis