Journal Watch - PD

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  • Cycler vs. Manual PD for Survival

    A systematic review and meta-analysis looked at 17 studies of more than 230,000 people for PD failure and all-cause mortality with cycler vs. manual PD. Both options had equivalent PD technique failure. But, there was a significant survival advantage for automated cycler PD.

    Read the abstract » | (added 2022-12-19)

    Tags: Peritoneal Dialysis, PD, Modality, Automated Peritoneal Dialysis, APD, Continuous Ambulatory Peritoneal Dialysis, CAPD, All cause Mortality, ACM, PD Failure, Survival

  • The Predictive Value of Early, Non-infectious PD Complications

    A prospective, multicenter cohort study of 1,596 people starting PD in New Zealand from 2014 to 2018 (inclusive) looked at survival and time on PD of those who had catheter-related exit site dialysate leaks or other leaks within 30 days of PD start. Peritonitis-free survival, first PD catheter survival, and tunnel infection free survival were secondary outcomes. Among the 102 with an early complication, overall mortality, the rate of stopping PD, and first catheter failure were all higher.

    Read the abstract » | (added 2022-11-16)

    Tags: PD, Survival, Peritonitis free Survival, First PD Catheter Survival, Tunnel Infection Free Survival, Early Catheter related Complication

  • Safety of Exercise for Those Who Do PD

    A review of 25 studies of exercise in PD found only minor adverse events, mainly short-term muscle or joint pain or fatigue. There were no serious adverse events or signs of harm.

    Read the abstract » | (added 2022-09-13)

    Tags: PD, Peritoneal Dialysis, Exercise, Benefits, Adverse Events

  • Too-high OR Too-low LDL Cholesterol and Survival on PD

    A retrospective study in China looked at data from 3,565 people starting PD from 2005 to 2020. Both higher and lower levels of LDL-C were linked with higher all-cause and cardiovascular mortality. Malnutrition and low LDL-C was especially risky.

    Read the abstract » | (added 2022-08-11)

    Tags: PD, LDL C, Cardiovascular Mortality, All cause Mortality, Malnutrition

  • Risk of Left Ventricular Hypertrophy Tied to Fluid Overload on PD

    A single hospital had 226 enrolled PD patients between late 2018 and January 2021. Using bioimpedance analysis and cardiac color Doppler ultrasound, patients were divided into an LVF and a non-LVF group, and into a normal volume and overhydration group. Of participants, 125 (55.3%) had LVH. Overhydration and low hemoglobin levels were independent risk factors for LVH.

    Read the abstract » | (added 2022-06-10)

    Tags: PD, LVH, Overhydration, Volume Loads

  • PD Reduced Hospitalization 24% vs. In-center HD with a Catheter

    In an 18-month retrospective study, 717 PD patients were matched 1:1 with in-center HD patients using central venous catheters. The matching also included cause of ESKD, race, diabetes status, and insurance. The hospitalization rate was 24% lower for those on PD, and mortality was 15% lower.

    Read the abstract » | (added 2022-04-18)

    Tags: PD, In center HD, Catheters, Cause Of ESKD, Race, Diabetes Status, Insurance, Hospitalization Rate, Mortality

  • The Impact of Vitamin D Levels on Quality of Life in PD

    Fifty people on PD were divided into a normal vitamin D (>20 ng/mL) and a deficient vitamin D group (<20 ng/mL), and both groups took the KDQOL-36 quality of life questionnaire. All subscales of the KDQOL-36 were significantly lower in the vitamin D deficient group.

    Read the abstract » | (added 2022-04-18)

    Tags: PD, Vitamin D, KDQOL 36

  • Must PD Stop when Residual Kidney Function is Gone?

    Not necessarily. In a small, physiological study (n=15) of anuric CAPD patients with low Kt/V, fluid status, dietary intake, and nitrogen removal were all assessed. All were able to maintain good nutritional status, with no symptoms of nitrogen retention and good volume control.

    Read the abstract » | (added 2022-02-14)

    Tags: PD, Residual Kidney Function, CAPD, Kt/V, Fluid Status, Dietary Intake, Nitrogen Removal, Volume Control

  • PD Helps Kidney Function Recovery

    PD is known to help preserve residual kidney function. A study of 981 people on PD and 12,619 on HD in Taiwan looked at which option was more likely to help incident dialyzors recover function. Nearly 5% did recover their kidney function within 3 years—with a better chance for those who did PD.

    Read the abstract » | (added 2022-02-14)

    Tags: PD, HD, Kidney Function Recovery

  • Standard vs. Incremental PD Start: 12-year Retrospective Study

    When people start PD with some residual function, is it beneficial not to begin with a full PD prescription? A study looked back at 12 years of people who started PD, 232 standard and 71 intermittent (iPD; 2-3 manual exchanges per day). Those who did iPD had higher residual kidney function than those on standard PD. For people with diabetes, iPD was linked with a survival advantage as well.

    Read the abstract » | (added 2021-12-16)

    Tags: PD, Residual Function, Intermittent PD, IPD, Diabetes