Journal Watch
Personalized PD Prescriptions
Urea alone is not able to assess dialysis adequacy. Rather than a focus on removing a single toxin, a more holistic, person-centered approach is emerging to improve well-being and minimize treatment burden—based on clinical outcomes and patient experiences of care. This approach requires close collaboration between patients and care teams and eliciting patient goals, priorities, and preferences. This paper reviews the evidence for a patient-centered approach to PD.
Read the abstract » | (added 2024-06-14)
Tags: Urea, Dialysis Adequacy, Treatment Burden, Patient centered Care, PD
IM-HOME Study Examines Barriers to Home Dialysis
A small advisory board of patients, care partners, and providers devised lists of perceived barriers to inform an online survey. Respondents ranked their top three barriers and described barriers. Among 298 patients and care partners, the top three barriers were fear, lack of space, and a need for support. Provider- (n=224) perceived barriers were quite different: poor patient education; limited support for home staff, mental health, and education; and lack of experienced staff.
Read the abstract » | (added 2024-06-14)
An Integrated Care Model Supports Home Dialysis
A new paper describes a model of care that prioritizes safe and effective use of home therapies, patient-centered care, informed decision-making, and comprehensive support. The integrated care framework emphasizes continuous quality improvement and helps to identify and assess patients, educate them, facilitate transitions between modalities, and consider the logistics of urgent dialysis starts. The aim is to create a seamless transition to home.
Read the abstract » | (added 2024-06-14)
Tags: Model Of Care, Home Therapies, Patient centered Care, Informed Decision making, And Comprehensive Support, Integrated Care Framework, Modality
Home HD, Self-cannulation, and Survival
An observational study of all home HD patients at a single center from 2001 to 2020 examined treatment survival and mortality. Among 77 self-cannulating patients dialyzing for a median of 18 hours per week, there were 11 deaths, largely cardiovascular, and 19 technique failures after 100 months, largely due to vascular access issues.
Read the abstract » | (added 2024-06-14)
Tags: Home HD, Self Cannulation, Treatment Survival, Mortality, Cardiovascular, Technique Failure, Vascular Access
Why Do Patients Switch from PD to HD?
In retrospective data from 5,224 DCI PD patients from 2010 to 2019 about 61% started with PD (PD-first), 18% switched from HD to PD in the first 90 days (PD-early), and 21% after 90 days (PD-late). Compared to PD-first patients, those who switched early or late had a higher risk of transfer to HD in the first 9 months. Additional risk factors included peritonitis, fewer home visits, lower serum albumin, lower residual kidney function, and lower PD clearance.
Read the abstract » | (added 2024-05-09)
Tags: PD first, PD early, PD late, Peritonitis, Serum Albumin, Residual Kidney Function, PD Clearance
Fluid Compartment Shifts and Post-hemodialysis Recovery Time
GENTLE ultrafiltration matters! A bioimpedance study analyzed data from 124 patients who had long (>1 hour) or short (<1 hour) recovery times after dialysis. Patients who had sessions with prolonged recovery time also reported more symptoms, psychological distress—and greater compartmental fluid shifts, as seen in extracellular water to total body water ratios.
Read the abstract » | (added 2024-05-09)
Tags: Ultrafiltration, Bioimpedance, Post hemodialysis Recovery Time, Fluid Compartment Shifts, Extracellular Water, Peri‐dialytic Symptoms
Does Social Deprivation Impact PD Outcomes?
A French registry (REIN) study examined data from 1,581 adult PD patients during the 18 months from January 1, 2017 to June 30, 2018, with observation completed in December, 2020. More than a quarter (418; 26.5%) were in Quintile 5 of the European Deprivation Index; the most deprived patients. Social deprivation was not associated with death or a composite event of death or transfer to HD.
Read the abstract » | (added 2024-05-09)
Tags: Social Deprivation, PD Outcomes, European Deprivation Index
Carbon Footprint of CAPD vs. CCPD/APD in Australia
In the U.S., CAPD has been losing ground to cycler PD for a decade or more. But, an Australian analysis finds that CAPD has about a one-third lower carbon footprint than use of a PD cycler. With Baxter equipment, the manufacture and disposal of PD fluids and consumables were estimated at 1,992 Kg CO2 equivalent emissions for cycler PD; and just 1,245 Kg CO2 equivalent emissions for manual PD.
Read the abstract » | (added 2024-05-09)
New Nomogram Predicts Roxadustat Treatment Failure in Anemic PD Patients
A retrospective analysis of 204 anemic PD patients from 2019 to 2023 was used to construct a predictive nomogram of Roxadustat success. Duration of PD, serum transferrin, cardiovascular comorbidities and stains were significant predictors. The nomogram was more predictive at 12 months than at 6 months.
Read the abstract » | (added 2024-04-12)
Tags: Roxadustat, HIF inhibitor, Treatment Failure, Anemia, PD
Mineral Bone Disease (MBD) and Survival on PD
A P-DOPPS study analyzed MBD data from more than 12,000 patients from eight countries. The results revealed a U-shaped curve for the relationship between PTH and mortality, with the lowest risk at PTH levels of 300-599 pg/mL. Serum calcium levels higher than 9.6 mg/dL were associated with a 20% increase in mortality as well. Major country variations in MBD treatment were identified.
Read the abstract » | (added 2024-04-12)
Tags: Mineral Bone Disease, MBD, PTH, Mortality, Serum Calcium Levels, PD